BMS-200 (BMS200;BMS 200) CAS No.: 1675203-82-3

BMS-200 (BMS200;BMS 200) CAS No.: 1675203-82-3

Chemical Structure : BMS-200
CAS No.: 1675203-82-3

Description

Chemical Structure : BMS-200

CAS No.: 1675203-82-3

product-337-100

 

BMS-200 (BMS200;BMS 200)

Catalog No.: URK-V2452 Only Used For Lab.

A potent PD-1/PD-L1 interaction inhibitor with IC50 of 80 nM in a homogenous time-resolved fluorescence binding assay..

 

Biological Activity

A potent PD-1/PD-L1 interaction inhibitor with IC50 of 80 nM in a homogenous time-resolved fluorescence binding assay.
BMS-200 have ability to modulate the immune system. By targeting specific immune cells, BMS-200 can help regulate immune activity and prevent unwanted inflammation. This makes it an ideal therapy for autoimmune diseases, which occur when the immune system attacks healthy cells and tissues in the body.
BMS-200 has been shown to have effective anti-tumor activity. Its ability to target and destroy cancer cells has been demonstrated in pre-clinical studies, and clinical trials are currently underway to investigate its potential as a cancer therapy.

 

Physicochemical Properties

M.Wt

499.511

Formula

C27H27F2NO6

CAS No.

1675203-82-3

Appearance

Solid

Storage

Solide Powder

-20 °C 3years;

4°C 2years

In Solvent

-80°C 6 Months

-20°C 1 Months

Solubility

Chemical Name

(S)-4-((4-((3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methylbenzyl)oxy)-2,5-difluorobenzyl)amino)-3-hydroxybutanoic acid

 

References

1. Guzik K, et al. J Med Chem. 2017 Jul 13;60(13):5857-5867.

2. Chupak, L.S., and Zheng, X. Compounds useful as immunomodulators. PCT/US2014/053695, (2015).

 

product-80-80

URK-V2452_COA

product-80-80

URK-V2452_SDS

product-80-80

URK-V2452_TDS

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