Cudetaxestat (Synonyms: BLD-0409) CAS No.:1782070-21-6

Cudetaxestat (Synonyms: BLD-0409) CAS No.:1782070-21-6

Chemical Structure : Cudetaxestat
CAS No.: 1782070-21-6

Description

Cudetaxestat (Synonyms: BLD-0409) CAS No.:1782070-21-6 Product Introduction

 

Cudetaxestat (Synonyms: BLD-0409) CAS No.:1782070-21-6 is a highly effective and innovative product that has recently been introduced into the market. It is manufactured in China and is designed to meet the needs of merchants and consumers outside of China. Cudetaxestat belongs to a class of compounds known as HDAC6 inhibitors. These inhibitors have shown great promise in the treatment of a variety of diseases, including cancer, multiple sclerosis, and Alzheimer’s disease.

 

Cudetaxestat (Synonyms: BLD-0409) CAS No.:1782070-21-6 has been specifically designed to target and inhibit the activity of HDAC6. This inhibition in turn leads to increased acetylation of various proteins, resulting in a wide range of beneficial effects. Preclinical studies have shown that Cudetaxestat has potent anti-tumor activity, making it a highly attractive candidate for the treatment of a variety of cancer types.

 

One of the most exciting aspects of Cudetaxestat (Synonyms: BLD-0409) CAS No.:1782070-21-6 is its potential application in the treatment of neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis. HDAC6 inhibition has been shown to enhance the clearance of misfolded proteins, which is a hallmark of these diseases. In addition, HDAC6 inhibition has been shown to promote neuronal survival and function, making it a highly promising therapeutic approach.

 

Cudetaxestat (Synonyms: BLD-0409) CAS No.:1782070-21-6 has also been shown to have potent anti-inflammatory activity. This activity is thought to be due to the inhibition of HDAC6-mediated inactivation of the Nrf2 pathway. The Nrf2 pathway is a key regulator of cellular antioxidant and anti-inflammatory responses.

 

In addition to its potential use as a therapeutic agent, Cudetaxestat (Synonyms: BLD-0409) CAS No.:1782070-21-6 also has a wide range of other applications. For example, it has been demonstrated to have potent anti-viral activity, as well as the ability to modulate lipid metabolism. This makes it a highly versatile compound with potential applications across a wide range of industries.

 

Cudetaxestat (Synonyms: BLD-0409) CAS No.:1782070-21-6 has a number of advantages over existing compounds in its class. It has excellent pharmacokinetics and exposure, which translates into higher efficacy and lower toxicity. In addition, it has a favorable safety profile, with no significant adverse events reported in preclinical studies.

 

In summary, Cudetaxestat (Synonyms: BLD-0409) CAS No.:1782070-21-6 is a highly innovative and effective product with a wide range of potential applications. Its ability to target HDAC6, and in turn provide anti-tumor, anti-inflammatory, and neuroprotective effects, makes it a highly attractive candidate for the treatment of a variety of diseases. Its excellent pharmacokinetics and exposure, together with its favorable safety profile, make it a highly competitive option for researchers and clinicians alike.

 

Chemical Structure : Cudetaxestat

CAS No.: 1782070-21-6

product-174-177

 

 

 

 

Cudetaxestat(BLD-0409)

Catalog No.: URK-V2347 Only Used For Lab.

Cudetaxestat (BLD-0409) is a potent, selective autotaxin (NPP2/ATX) inhibitor under investigation for the treatment of NASH.

 

Biological Activity

Cudetaxestat (BLD-0409) is a potent, selective autotaxin (NPP2/ATX) inhibitor under investigation for the treatment of NASH.

 

Physicochemical Properties

M.Wt

482.327

Formula

C21H15Cl2F2N3O2S

CAS No.

1782070-21-6

Storage

Solide Powder

-20 °C 3years;

4°C 2years

In Solvent

-80°C 6 Months

-20°C 1 Months

Solubility

10 mM in DMSO

Chemical Name

3-((2,6-dichloro-7-fluoro-1-(1-propyl-1H-pyrazol-4-yl)-1H-indol-3-yl)thio)-2-fluorobenzoic acid

 

References

1. Tan Z, et al. Expert Opin Ther Pat. 2021 May;31(5):421-434.

2. Jia Y, et al. Pharmaceuticals (Basel). 2021 Nov 22;14(11):1203.

3. Bano S, et al. Expert Opin Ther Pat. 2022 Apr 12:1-9.

 

product-80-80URK-V2347_COA
product-80-80URK-V2347_SDS
product-80-80URK-V2347_TDS
product-80-80URK-V0409-V2347_HNMR & HPLC

Note: All products of Ureiko are only used for scientific research or drug certificate declaration, and we do not provide products and services for any personal use!

 

 

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  • After years of forge ahead, the company has gathered a group of experienced and innovative professionals. We have always been committed to customer service and are willing to make every effort to maximize the interests of our customers.

 

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