ARV-471 CAS No.:2229711-08-2

Introduction to ARV-471:

ARV-471 is a highly specialized product that has been specifically designed for the modern-day requirements of businesses around the world. It is a substance that has been created with a unique blend of ingredients that makes it highly effective in its application. ARV-471 is a specialized chemical compound that can be used for a wide range of purposes. Its versatile properties make it the ideal choice for businesses operating in a variety of industries.

What is ARV-471?

ARV-471 is a specialized chemical compound that has been specifically designed to meet the modern-day requirements of businesses globally. It is an advanced polymer compound that is highly flexible and can be used for a range of industrial applications. ARV-471 is a specialized substance that is highly resistant to chemicals and other environmental factors. This makes it highly effective for a diverse range of applications.

Features of ARV-471:

1. High Flexibility - ARV-471 is highly flexible and can be molded into various shapes and sizes. This makes it ideal for use in a wide range of applications.

2. Durable - ARV-471 has high durability that makes it effective in the long term. Its high resistance to UV light, chemicals and other environmental factors means it can withstand harsh weather conditions and other factors.

3. Anti-corrosion - ARV-471 is highly resistant to corrosion, making it the ideal choice for applications that require protection from environmental factors.

4. Water Resistant - ARV-471 is highly water-resistant and is capable of withstanding exposure to water without sustaining damage. This makes it suitable for use in water-based applications.

5. High-Temperature Resistance - ARV-471 is highly heat-resistant, making it ideal for use in applications that require exposure to high temperatures.

Applications of ARV-471:

1. Electrical Equipment - ARV-471 is widely used in the manufacture of electrical equipment such as circuit boards, cables, and connectors. Its high flexibility and durability make it the ideal choice for these applications.

2. Automotive Industry - ARV-471 is used extensively in the automotive industry. Its anti-corrosion and high-temperature resistance properties make it ideal for use in critical components such as engine parts and brakes.

3. Aerospace Industry - ARV-471 is used in the aerospace industry for its durability and high-temperature resistance properties. It can withstand the harsh environmental conditions encountered during space travel.

4. Sports Equipment - ARV-471 is used in the manufacture of sports equipment such as helmets and protective gear. Its durability and anti-corrosion properties make it ideal for such applications.

Conclusion:

ARV-471 is a specialized substance that has been carefully formulated to meet the current-day requirements of businesses around the world. Its superior properties make it the ideal choice for a wide range of applications ranging from automotive, aerospace to electrical equipment. ARV-471 is a versatile product that offers many benefits to businesses worldwide. Ensuring that it is included in their products will be the smart choice for entrepreneurs who want to get ahead in the market.

Chemical Structure : ARV-471

CAS No.: 2229711-08-2

 

 

 

 

ARV-471 (ARV 471, ARV471)

Catalog No.: URK-V791 Only Used For Lab.

ARV-471, an ER-targeting protein degrader for breast cancer, is a hetero-bifunctional molecule that facilitates the interactions between estrogen receptor alpha and an intracellular E3 ligase complex, leading to the ubiquitylation and subsequent degradation of estrogen receptors via the proteasome.

Biological Activity

ARV-471, an ER-targeting protein degrader for breast cancer, is a hetero-bifunctional molecule that facilitates the interactions between estrogen receptor alpha and an intracellular E3 ligase complex, leading to the ubiquitylation and subsequent degradation of estrogen receptors via the proteasome. ARV-471 robustly degrades ER in ER-positive breast cancer cell lines with a half-maximal degradation concentration (DC50) of ~ 1 nM. PROTAC-mediated ER degradation decreases the expression of classically-regulated ER-target genes and inhibits cell proliferationof ER-dependent cell lines (MCF7, T47D).

Physicochemical Properties

References

URK-V791_COA

URK-V791_SDS

 

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