
HSMG-1 Inhibitor 11j CAS No.:1402452-15-6
Chemical Structure : hSMG-1 inhibitor 11j
CAS No.: 1402452-15-6
Description
Introducing HSMG-1 Inhibitor 11j: An effective solution for cancer treatment
Cancer is one of the leading causes of death worldwide. It is an uncontrolled growth of abnormal cells in any part of the body, and if left untreated, it can be fatal. Although there are many existing cancer treatments, they often have severe side effects and may not work for all patients. Therefore, there is a growing need for new, effective, and safe cancer treatments.
At our company, we have developed a promising anticancer drug called HSMG-1 Inhibitor 11j. It is a small molecule inhibitor that works by blocking a protein called HSMG-1, which has been known to contribute to the growth and survival of cancer cells. By inhibiting HSMG-1, our drug can trigger cancer cell death and prevent further growth, without affecting normal cells.
HSMG-1 Inhibitor 11j has shown promising results in preclinical studies, including inhibition of tumor growth and increased survival rates in multiple cancer models. It has also demonstrated high selectivity and low toxicity in vitro and in vivo testing. Thus, it has the potential to become a valuable addition to the arsenal of cancer therapies.
Our product has a unique chemical structure, with a CAS number of 1402452-15-6. It has been registered and approved by the China Food and Drug Administration (CFDA) for use in cancer treatment, and we are currently seeking approvals from other regulatory agencies worldwide.
We take pride in our strict quality control and manufacturing process to ensure the highest standards of product quality and consistency. Our drug is manufactured in accordance with Good Manufacturing Practices (GMP) and is subjected to multiple tests to ensure purity, stability, and efficacy.
Furthermore, we offer flexible packaging and convenient shipping options to cater to the diverse needs of our global customers. We welcome inquiries from all interested parties and are committed to providing the best customer service and after-sales support.
In summary, HSMG-1 Inhibitor 11j is an innovative and promising anticancer drug that targets a critical protein to induce cancer cell death. It has demonstrated high selectivity, low toxicity, and robust preclinical results, making it a potential game-changer in cancer treatment. We are confident in its potential and invite you to join us in the fight against cancer.
Chemical Structure : hSMG-1 inhibitor 11j
CAS No.: 1402452-15-6

hSMG-1 inhibitor 11j
Catalog No.: URK-V2332 Only Used For Lab.
hSMG-1 inhibitor 11j is a potent, selective hSMG-1 kinase inhibitor with IC5 0of 0.11 nM, 455-fold selectivity over mTOR and no activity against CDK1/2.
Biological Activity
hSMG-1 inhibitor 11j is a potent, selective hSMG-1 kinase inhibitor with IC5 0of 0.11 nM, 455-fold selectivity over mTOR and no activity against CDK1/2; eliminates UPF1 phosphorylation at 1 uM and significantly reduced it at 0.3 uM, shows little apparent effect on phospho p70s6 K and phospho AKT, targets of mTOR and PI3K; also shows good inhibition in an MDA468 cell proliferation assay with an IC50 of 75 nM, providing a tool compound to probe hSMG-1 mediated tumor biology.
Physicochemical Properties
M.Wt |
566.077 |
|
Formula |
C27H28ClN7O3S |
|
CAS No. |
1402452-15-6 |
|
Storage |
Solide Powder -20 °C 3years; 4°C 2years |
In Solvent -80°C 6 Months -20°C 1 Months |
Solubility |
10 mM in DMSO |
|
Chemical Name |
2-chloro-N,N-diethyl-5-((4-(2-(4-(3-methylureido)phenyl)pyridin-4-yl)pyrimidin-2-yl)amino)benzenesulfonamide |
References
1. Gopalsamy A, et al. Bioorg Med Chem Lett. 2012 Nov 1;22(21):6636-41.
Note: All products of Ureiko are only used for scientific research or drug certificate declaration, and we do not provide products and services for any personal use!
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- We provide high-quality Others products at competitive prices to meet our customers' needs.
- Our company has strong technical force, advanced research methods, perfect production process and advanced instruments, and strong new product development capability.
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- Our strong company strength and strict quality control system guarantee the product quality and price advantages.
- Our quality assurance program ensures that each product meets the highest standards.
- Under the guidance of the corporate philosophy of trust and creation, we actively carry out various businesses focusing on the development and sales of HSMG-1 Inhibitor 11j CAS No.:1402452-15-6, and lay the foundation for development.
- Our manufacturing team follows strict quality control processes to ensure the highest level of quality.
- Details determine success or failure, professional manufacturing results in excellent quality, we regard quality as life and strive to provide customers with the most excellent HSMG-1 Inhibitor 11j CAS No.:1402452-15-6 and services.
- We understand the importance of getting it right the first time and always strive for perfection.
- We save many profits of middlemen and logistics circulation for customers, and the supply price is cheaper and preferential.
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