SR 11302 CAS No.:160162-42-5

SR 11302 CAS No.:160162-42-5 is a high-quality product manufactured by our company located in China. It is a pyrido[2,3-d]pyrimidine derivative that has found widespread use in the pharmaceutical industry. The compound has a molecular weight of 349.34 g/mol, and its molecular formula is C19H15N5O.

As a manufacturer of SR 11302, we have undertaken rigorous quality control measures to ensure that the product meets the highest standards of purity, stability, and safety. We use advanced analytical techniques to verify the identity and purity of the product, and we continually monitor its stability to ensure that it meets the requirements of our customers. Our commitment to quality has earned us a reputation for reliability and excellence in the industry.

The product shows promise in the development of new drugs for conditions like cancer, cardiovascular disease, and neurological disorders. SR 11302 works by inhibiting the activity of the enzyme cyclin-dependent kinase 4/6 (CDK4/6), which plays a crucial role in cell division, proliferation, and survival. By blocking this enzyme, SR 11302 can prevent the growth and spread of cancer cells and has been shown to have significant anti-tumor activity in preclinical models.

SR 11302 has also been studied for its potential use in treating diseases of the central nervous system, such as Alzheimer's and Parkinson's disease. CDKs have been implicated in the pathological changes that occur in these conditions, and inhibitors like SR 11302 may have therapeutic benefits in halting or reversing the progression of these diseases.

In addition to its potential therapeutic uses, SR 11302 may also be of interest to researchers and drug development companies for use in screening assays and other preclinical studies. The compound has been shown to have good solubility and stability, making it an attractive tool for use in drug discovery and optimization.

Overall, SR 11302 is a highly valuable product with significant potential in the pharmaceutical industry. As a manufacturer, our commitment to quality and excellence ensures that our customers receive a reliable supply of this essential compound for use in their research, drug discovery, and development efforts. We are confident that our product will meet the high standards and exacting requirements of our customers and look forward to working with merchants worldwide to provide them with the best possible service and support.

Chemical Structure : SR-11302

CAS No.: 160162-42-5

 

SR-11302(SR11302)

Catalog No.: URK-V2319 Only Used For Lab.

SR-11302( SR11302) is a specific, small molecule inhibitor of activator protein-1 (AP-1), inhibits AP-1 activity without activating the transcription of RARE.

Biological Activity

SR-11302( SR11302) is a specific, small molecule inhibitor of activator protein-1 (AP-1), inhibits AP-1 activity without activating the transcription of RARE.
SR-11302 inhibits tumor promotion in AP-1-luciferase transgenic mice, inhibits papilloma formation during the course of the tumor promotion. SR-11302 blocks TPA-induced AP-1 transactivation in AP-1-luciferase transgenic mice.
SR-11302 decreases VEGF promoter activity and downregulates c-Fos expression and release.
SR-11302 reduces metastatic lesion formation in the 4D model of lung cancer.

Physicochemical Properties

References

1. Maron BA, et al. Circulation. 2014 Jul 8;130(2):168-79.

2. Huang C, et al. Proc Natl Acad Sci U S A. 1997 May 27;94(11):5826-30.

3. Li JJ, et al. Cancer Res. 1997 Aug 15;57(16):3569-76.

4. Catar R, et al. Kidney Int. 2013 Dec;84(6):1119-28.

URK-V2319_COA

URK-V2319_SDS

URK-V2319_TDS

 

Note: All products of Ureiko are only used for scientific research or drug certificate declaration, and we do not provide products and services for any personal use!

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