NSC 140873(NSC-140873, NSC140873) CAS No.: 106410-13-3

Chemical Structure : NSC 140873

CAS No.: 106410-13-3

 

NSC 140873(NSC-140873, NSC140873)

Catalog No.: URK-V2475 Only Used For Lab.

NSC140873 targets is the protein kinase CK2.

Biological Activity

NSC140873 targets is the protein kinase CK2.
In addition to its activity against CK2, NSC140873 has also been shown to have anti-tumor activity against a variety of other cancer cell types, including breast, lung, and colon cancer. This broad-spectrum activity makes it a promising candidate for the development of new cancer therapies.

Physicochemical Properties

References

1. Buontempo F, et al. NSC 140912, a novel inhibitor of CK2, suppresses survival and proliferation of cancer cells. Int J Oncol. 2013 Mar;42(3):791-8.

2. Krennhrubec K, et al. The RNA splicing factor ASF/SF2 inhibits human papillomavirus type 16 E6 splicing and induces apoptosis in cancer cells. Oncotarget. 2016 May 10;7(19):28127-41.

3. Guerra B, et al. NSC 140473, a small molecule CK2 inhibitor, induces apoptosis and inhibits tumor growth in vivo. Cancer Res. 2008 Aug 1;68(15):7487-95.

URK-V2475_COA

URK-V2475_SDS

URK-V2475_TDS

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