GLPG3970 (GLPG 3970, GLPG-3970) CAS No.: 2403733-82-2

GLPG3970 (GLPG 3970, GLPG-3970) CAS No.: 2403733-82-2

Chemical Structure : GLPG3970
CAS No.: 2403733-82-2

Description

Chemical Structure : GLPG3970

CAS No.: 2403733-82-2

product-294-146

 

GLPG3970 (GLPG 3970, GLPG-3970)

Catalog No.: URK-V2450 Only Used For Lab.

GLPG3970 (GLPG 3970) is a potent, selective first-in-class salt inducible kinase SIK2/SIK3 inhibitor in development for inflammatory indications.

 

Biological Activity

GLPG3970 works by selectively blocking a protein called JAK1, which plays a pivotal role in the immune system. By inhibiting JAK1, GLPG3970 can reduce inflammation and alleviate symptoms of IBD, such as diarrhea, abdominal pain, and rectal bleeding.
Preclinical studies have demonstrated that GLPG3970 is highly potent and selective in inhibiting JAK1 activity.

 

Physicochemical Properties

M.Wt

504.51

Formula

C25H27F3N4O4

CAS No.

2403733-82-2

Appearance

 

Storage

Solide Powder

-20 °C 3years;

4°C 2years

In Solvent

-80°C 6 Months

-20°C 1 Months

Solubility

 

Chemical Name

O=C1C2=C(CCN1CC(F)(F)F)C=C(C3=CN=C4C=C(C=CN43)OCCN5CCOCC5)C=C2OC

 

References

 

product-80-80

URK-V2450_COA

product-80-80

URK-V2450_SDS

product-80-80

URK-V2450_TDS

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