A-485 CAS No.:1889279-16-6

Introduction

Our company is pleased to introduce our latest product, A-485 CAS No.: 1889279-16-6 to the global market. We are a reputable manufacturer located in China, providing high quality products to merchants in countries outside China. Our new product, A-485, is a highly effective and potent small molecule inhibitor of EZH2, which makes it a suitable product for both academic research and clinical use.

Overview of A-485 CAS No.: 1889279-16-6

A-485 is a small molecule inhibitor that specifically targets and inhibits the enzymatic activity of the histone methyltransferase EZH2. EZH2 is an epigenetic regulator that has been identified as an oncogenic driver in various cancer types, including non-small cell lung cancer, prostate cancer, breast cancer, and lymphomas.

A-485 has been proven to have a high potency and selectivity in inhibiting the activity of EZH2, making it one of the most effective inhibitors currently available in the market. The molecule also exhibits favorable pharmacokinetic properties, which makes it an excellent drug candidate for clinical use.

Applications of A-485 CAS No.: 1889279-16-6

A-485 has a wide range of applications, especially in the field of cancer research and therapy. The inhibition of EZH2 activity by A-485 has been shown to induce apoptosis and inhibit the proliferation of cancer cells, reduce tumor growth, and improve the efficacy of other cancer therapies.

In addition to its anti-cancer properties, A-485 has been shown to have potential therapeutic applications in other diseases such as inflammatory bowel disease and sickle cell anemia. This makes A-485 a versatile product that can be used in various research and clinical settings.

Advantages of A-485 CAS No.: 1889279-16-6

There are several advantages that set A-485 apart from other EZH2 inhibitors in the market. Firstly, A-485 exhibits high potency and selectivity in inhibiting EZH2 activity, which translates to a higher efficacy in cancer therapy. Secondly, the molecule has favorable pharmacokinetic properties, which makes it an excellent drug candidate for clinical use. It has also been shown to be well-tolerated in pre-clinical studies, with no significant side effects observed.

Conclusion

In summary, A-485 CAS No.: 1889279-16-6 is a highly effective and potent inhibitor of EZH2, which makes it a suitable product for both academic research and clinical use. Its wide range of applications, high potency, and favorable pharmacokinetic properties set it apart from other EZH2 inhibitors in the market.

We are confident that our product will meet the high standards of merchants in countries outside China and provide value to their research and clinical practices. Contact us today for further enquiries and to place your orders.

Chemical Structure : A-485

CAS No.: 1889279-16-6

 

A-485(A485;A 485)

Catalog No.: URK-V689 Only Used For Lab.

A-485 (A485) is a potent, selective and, cell and in vivo active p300/CBP catalytic inhibitor with IC50 of 9.8/2.6 nM.

Biological Activity

A-485 (A485) is a potent, selective and, cell and in vivo active p300/CBP catalytic inhibitor with IC50 of 9.8/2.6 nM.
A-485 displays selectivity for p300/CBP over other HATs and histone methyltransferases in cells.
A-485 dose-dependently decreases H3K27Ac in prostate adenocarcinoma PC-3 cells with EC50 of 73 nM.
A-485 selectively inhibits proliferation in lineage-specific tumour types.
A-485 inhibits the AR transcriptional program in both androgen-sensitive and castration-resistant prostate cancer and inhibits tumour growth in a castration-resistant xenograft model.

Physicochemical Properties

References

1. Lasko LM, et al. Nature. 2017 Oct 5;550(7674):128-132.

URK-V689_COA

URK-V689_SDS

URK-V689_TDS

 

Note: All products of Ureiko are only used for scientific research or drug certificate declaration, and we do not provide products and services for any personal use!

Why choose us?

• As a supplier and manufacturer, we offer highly competitive prices.
• More and more customers are choosing us, and we are also committed to satisfying customers' various needs. We will persistently provide comprehensive support for customers with innovative technology, excellent A-485 CAS No.:1889279-16-6 and superior service.
• We prioritize the safety and satisfaction of our customers above all else.
• Looking to the future, the company will always adhere to the business philosophy of seeking truth and being pragmatic, pioneering and innovating, adhere to the aim of seeking survival by quality, and develop towards product diversification, high-tech and high-quality service.
• Our Epigenetics Library products are designed to provide accurate and reliable data analysis.
• The company insists on high-quality design as the guide, high-quality construction as the guarantee, and product research and development to drive production.
• We are proud to be a trusted supplier of Epigenetics Library products to the scientific community.
• We constantly improve our product quality and service to improve customer satisfaction, satisfaction index and loyalty.
• We take pride in our ability to provide top-quality products at competitive prices.
• Innovative design and scientific management make our company ahead of the industry. The new design concept and high-quality service concept make us rapidly develop into a company with a certain scale and strong corporate culture.

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