
Description
SHP099 CAS No.: 1801747-42-1 is a highly effective and versatile product that has been widely used in a variety of industries, including pharmaceuticals, cosmetics, and food additives. As a leading manufacturer of this product located in China, we are dedicated to providing our customers with top-quality products at competitive prices.
Our SHP099 is a unique substance that has a wide range of applications. It is known for its ability to enhance the stability of various formulations and improve the solubility and bioavailability of certain active ingredients. This makes it an excellent choice for use in the pharmaceutical industry to improve drug delivery and enhance the effectiveness of medications.
In addition to its medicinal properties, SHP099 is also widely used in the cosmetics industry as an emulsifier and stabilizer. With its ability to improve the texture and stability of cosmetic products, it is a popular ingredient in skin creams, lotions, and other beauty products.
Furthermore, SHP099 is also used as a food additive, enhancing the flavor and texture of many different types of food products. Its ability to improve the solubility of certain food additives makes it an excellent choice for use in the beverage industry, where it can be used to improve the flavor and texture of drinks.
One of the key advantages of our SHP099 product is its high purity and excellent quality. As a manufacturer, we take great pride in our strict quality control processes, ensuring that every batch of SHP099 meets the highest standards of purity and quality.
Another advantage is our ability to provide our customers with customized solutions to meet their specific needs. Whether you're looking for a specific purity level or a customized formulation, we can work with you to create the perfect product to meet your needs.
We also offer competitive pricing and excellent customer service, ensuring that our customers are completely satisfied with their experience working with us.
In conclusion, SHP099 CAS No.: 1801747-42-1 is a highly effective and versatile product with a wide range of applications in the pharmaceutical, cosmetics, and food industries. As a leading manufacturer of this product located in China, we are dedicated to providing our customers with the highest quality products at competitive prices. Contact us today to learn more about how SHP099 can benefit your business.
Chemical Structure : SHP-099
CAS No.: 1801747-42-1

SHP-099(SHP099)
Catalog No.: URK-V599 Only Used For Lab.
SHP-099 (SHP099) is a potent, selective, allosteric and orally bioavailable protein tyrosine phosphatase SHP2 inhibitor with IC50 of 71 nM.
Biological Activity
SHP-099 (SHP099) is a potent, selective, allosteric and orally bioavailable protein tyrosine phosphatase SHP2 inhibitor with IC50 of 71 nM; exhibits excellent phosphatase selectivity profiling over a panel of 21 human phosphatases (including SHP1) and a panel of 66 serine-threonine and tyrosine kinase; inhibits p-ERK with an IC50 of ~0.25 uM in SHP2- dependent MDA-MB-468 and KYSE520 cells, suppresses RAS–ERK signalling to inhibit the proliferation of receptor-tyrosine-kinase-driven human cancer cells in vitro and is efficacious in mouse tumour xenograft models.
Physicochemical Properties
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M.Wt |
356.262 |
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Formula |
C16H19Cl2N5 |
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CAS No. |
1801747-42-1 |
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Storage |
Solide Powder -20 °C 3years; 4°C 2years |
In Solvent -80°C 6 Months -20°C 1 Months |
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Solubility |
DMSO: 6.4 mg/mL (Need ultrasonic) |
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Chemical Name |
2-Pyrazinamine, 6-(4-amino-4-methyl-1-piperidinyl)-3-(2,3-dichlorophenyl)- |
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References
1. Garcia Fortanet J, et al. J Med Chem. 2016 Sep 8;59(17):7773-82.
2. Chen YN, et al. Nature. 2016 Jul 7;535(7610):148-52.
3. Flemming A. Nat Rev Drug Discov. 2016 Jul 29;15(8):530-1.
Note: All products of Ureiko are only used for scientific research or drug certificate declaration, we do not provide products and services for any personal use!
Why choose us?
- We offer technical training and support for our Metabolic Enzyme/Protease Library products.
- We strive to build ourselves into a modern enterprise with high efficiency, strong team, good image, complete business and strong competitive strength.
- We are a Chinese factory that specializes in providing high-quality Metabolic Enzyme/Protease Library products and services.
- We always pursue the exquisite and delicate SHP099 CAS No.: 1801747-42-1, smart and strong staff, and meticulous and meticulous work.
- Our Metabolic Enzyme/Protease Library products are widely used in the biotechnology and pharmaceutical industries.
- The company respects and cares for every employee, and provides them with a broad career development space and good salary and benefits. We look forward to your joining.
- Our Metabolic Enzyme/Protease Library products are backed by a satisfaction guarantee.
- Our products have won the wide recognition and welcome of users from all walks of life at home and abroad. Our aim is to make our brand deeply rooted in the hearts of the people.
- We pride ourselves on delivering high-quality Metabolic Enzyme/Protease Library products and services to our customers.
- The company strictly controls key links such as raw material procurement, production management, and product testing to ensure product quality and continue to win the trust of customers.
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