
Description
Introduction:
As a renowned manufacturer in China, we are pleased to introduce our revolutionary product, known as KAN0438757 CAS No.: 1451255-59-6. This product is slated to change the game in the wholesale industry as it presents a host of unique features that are highly sought after by merchants worldwide. If you are searching for a high-quality product that is both reliable and efficient, you have come to the right place.
KAN0438757 CAS No.: 1451255-59-6 is a product that has been designed with the utmost precision, using modern technology and the finest materials. Our product is not only of the highest quality but also highly affordable, making it an attractive option for merchants looking to improve their bottom line. Below we will explore some of the unique features of our product that make it stand out and an ideal choice for merchants looking to grow their business:
1. High Purity:
Our KAN0438757 CAS No.: 1451255-59-6 product has an extremely high purity rate, which is a critical feature for merchants looking for quality products that provide consistent results. Our product undergoes stringent quality control measures that ensure our products are of the highest caliber and consistently exceed industry standards.
2. Versatility:
Our KAN0438757 CAS No.: 1451255-59-6 product is highly versatile and can be used in a variety of applications, making it ideal for merchants who want a product that can be incorporated into their existing product lines. Our product is perfect for use in chemical laboratories, research institutions, and other applications that require the addition of high-quality chemicals.
3. Competitive Pricing:
We are committed to providing our clients with quality products that are affordable. Our KAN0438757 CAS No.: 1451255-59-6 product is priced competitively, making it an attractive option for merchants looking to reduce their overhead costs and improve their bottom line.
4. Highest Quality:
Quality is at the forefront of our product development process. We understand the importance of delivering quality products to our clients, and we achieve this by using only the finest materials and modern technology. Our stringent quality control measures ensure that our KAN0438757 CAS No.: 1451255-59-6 product meets the highest standards of quality.
5. Great Customer Support:
We are committed to providing our clients with exceptional customer support. Our team of experts is always available to answer any questions you may have and provide you with assistance every step of the way. Our goal is to build long-lasting relationships with our clients by delivering quality products and top-notch customer service.
Conclusion:
In conclusion, our KAN0438757 CAS No.: 1451255-59-6 product is a game-changer that offers merchants a host of unique features that are highly sought after in the industry. From high purity to affordability and versatility, our product is an excellent choice for merchants looking to improve their bottom line and grow their business. We are committed to providing our clients with quality products and exceptional customer support, and we look forward to partnering with you on this exciting journey.
Chemical Structure : KAN0438757
CAS No.: 1451255-59-6

KAN0438757(KAN 0438757;KAN-0438757)
Catalog No.: URK-V610 Only Used For Lab.
KAN0438757 (KAN-0438757) is a potent, selective PFKFB3 inhibitor, the ester prodrug of KAN0438241 with enhanced cell permeability.
Biological Activity
KAN0438757 (KAN-0438757) is a potent, selective PFKFB3 inhibitor, the ester prodrug of KAN0438241 with enhanced cell permeability.
KAN0438757 impairs recruitment of ribonucleotide reductase M2 and deoxynucleotide incorporation upon DNA repair, and reduces dNTP levels.
KAN0438757 selectively inhibits proliferation of transformed cells while sparing nontransformed cells.
KAN0438757 demonstrates significant suppression of intracellular F-2,6-P2 levels with sub µM IC50 values in cell lines representing pancreatic, gastric, and colon cancer (IC50=0.24 uM in Mia Paca-2 cells).
Physicochemical Properties
|
M.Wt |
447.433 |
|
|
Formula |
C21H18FNO7S |
|
|
CAS No. |
1451255-59-6 |
|
|
Storage |
Solide Powder -20 °C 3years; 4°C 2years |
In Solvent -80°C 6 Months -20°C 1 Months |
|
Solubility |
10 mM in DMSO |
|
|
Chemical Name |
2-hydroxyethyl 4-((5'-fluoro-2'-hydroxy-[1,1'-biphenyl])-3-sulfonamido)-2-hydroxybenzoate |
|
References
1. Gustafsson NMS, et al. Nat Commun. 2018 Sep 24;9(1):3872.
Note: All products of Ureiko are only used for scientific research or drug certificate declaration, and we do not provide products and services for any personal use!
Why choose us?
- We are committed to providing affordable Others products without compromising on quality.
- We have established a comprehensive pre-sales and after-sales service standards for our KAN0438757 CAS No.: 1451255-59-6.
- Our dedication to quality has earned us a loyal customer base.
- In the product development and design, we have achieved pioneering and breakthrough, and directly connect with international products with rich and diversified products.
- We believe in building strong relationships with our customers based on trust and mutual respect.
- We are adhering to the tenet of "make customers more satisfied when they use it than when they buy". Every customer's satisfaction with the use of our products will bring us a great sense of accomplishment. Our goal is to provide customers with competitive prices. Provide first-class quality products.
- We offer fast turnaround times and prompt delivery to meet our customers' deadlines.
- We integrate the gene of innovation into our own development blood.
- We understand the importance of getting it right the first time and always strive for perfection.
- With the effort to keep pace with world's trend, we'll always endeavor to meet customers' demands.
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