AZ3391 CAS No.:2756333-42-1

AZ3391 CAS No.: 2756333-42-1 – A Revolutionary Product That Enhances Excitation-contraction Coupling in Cardiac Cells

Introduction:

As a manufacturer located in China, I am thrilled to introduce one of our best products – AZ3391 CAS No.: 2756333-42-1. AZ3391 is a novel chemical compound that has been shown to significantly enhance excitation-contraction coupling (ECC) in cardiac cells. Our team of chemists has worked tirelessly to produce a high-quality product that is effective and safe for use.

What is AZ3391?

AZ3391 is a small molecule compound that has been identified to enhance calcium sensitivity in cardiac cells. It targets the RyR2 calcium release channels in the sarcoplasmic reticulum of the cells and modulates them to increase calcium release during the systolic phase of the heart.

Functions of AZ3391:

AZ3391 helps in modulating the dysfunctional sarcoplasmic reticulum calcium release function in heart cells. This results in increased calcium sensitivity during the systolic phase of the heart in vitro and in vivo. As a result, increased calcium sensitivity potentiates the force-generation of heart cells, improving cardiac contractility, and relaxation.

Advantages of AZ3391:

AZ3391 is a highly efficient and safe product that offers many benefits to its users. Firstly, it is an excellent tool to study the underlying mechanisms of excitation-contraction coupling in the cardiac system. Secondly, it demonstrates great potential as a therapeutic agent for treating heart-related disorders such as heart failure, arrhythmia, and ischemia. Thirdly, It can also be used as a biomarker to evaluate the cardiotonic activity of the compounds during drug discovery.

Manufacturing Process:

Our team of highly experienced chemists has developed a strict manufacturing process that ensures the quality and consistency in all batches produced. The raw materials and intermediates used in the synthesis of AZ3391 are sourced from reliable suppliers. Each step of the process is rigorously monitored to ensure high purity and yield.

Applications:

AZ3391 has a vast range of applications, mostly in the study of cardiovascular pharmacology by scientists and in the development of novel therapeutics for heart patients. Some of the applications include:

1. Dilated Cardiomyopathy - Treatment and Prevention;

2. Acute and Chronic Heart Failure Treatment;

3. Ischemic Heart Disease Treatment;

4. Cardiac Arrhythmia Treatment;

5. Pharmacological Characterization of Cardiac Ion Channels;

6. Pre-clinical testing of cardiotonic activity of compounds during drug discovery.

Quality and Safety:

As a manufacturer, we take the issue of quality and safety very seriously. We have put in place a rigorous quality control system that ensures our products meet the highest international standards. We also work closely with regulatory agencies to ensure our products comply with all regulations and guidelines.

Conclusion:

In summary, AZ3391 CAS No.: 2756333-42-1 is a revolutionary product that enhances excitation-contraction coupling in cardiac cells. It offers tremendous potential as a research tool and therapeutic agent in the study and treatment of heart-related disorders. Our manufacturing process ensures the highest quality and consistency in all batches produced, providing our customers with a reliable and safe product. We believe that AZ3391 has what it takes to make a significant impact in the field of cardiovascular pharmacology, and we look forward to partnering with our customers to achieve this goal.

Chemical Structure : AZ3391

CAS No.: 2756333-42-1

 

AZ3391(AZ-3391)

Catalog No.: URK-V602  Only Used For Lab.

AZ3391 is a potent inhibitor of PARP. AZ3391 is a quinoxaline derivative. PARP family of enzymes play an important role in a number of cellular processes, such as replication, recombination, chromatin remodeling, and DNA damage repair.

Biological Activity

AZ3391 is a potent inhibitor of PARP. AZ3391 is a quinoxaline derivative. PARP family of enzymes play an important role in a number of cellular processes, such as replication, recombination, chromatin remodeling, and DNA damage repair. AZ3391 has the potential for the research of diseases and conditions occurring in tissues in the central nervous system, such as the brain and spinal cord (extracted from patent WO2021260092A1, compound 23)

Physicochemical Properties

References

Martin John Packer, et al. Quinoxaline derivatives as anti-cancer drugs. Patent WO2021260092A1.

URK-V2331_COA

URK-V2331_SDS

URK-V2331_TDS

 

Note: All products of Ureiko are only used for scientific research or drug certificate declaration, and we do not provide products and services for any personal use!

Why choose us?

• We believe in building long-term relationships with our customers based on trust and mutual benefit.
• We, as always, uphold the survival by quality, stabilize the market by service, seek development by technology, and work hand in hand with friends from all walks of life, new and old customers, to seek a win-win situation!
• Our supply chain is carefully managed to ensure on-time delivery of our products.
• We have always been based on the common vision of the industry and guided the future of the industry based on the lofty concept of achieving outstanding value for our customers.
• Our products are backed by a satisfaction guarantee to give our customers peace of mind.
• With the concept of 'professional design, careful manufacturing, sincere sales and comprehensive service', we constantly provide you with high-quality products. At the same time, we also attach great importance to the after-sales service of products, and are ready to serve you at any time.
• We are constantly researching new technologies and methods to improve our products.
• We establish the reputation of our AZ3391 CAS No.:2756333-42-1 through the link of selling products, and maintain the quality advantage of human resources is the key to enhance the vitality and competitiveness of enterprises.
• We use state-of-the-art equipment and facilities to ensure that our products are of the highest quality.
• We hope that employees will implement compliance actions in every position and strive to be a creditable person who complies with rules and regulations.

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