
Description
Introduction
MK-1775 CAS No.:955365-80-7 is a potent and selective small molecule inhibitor that targets the checkpoint kinase 1 (Chk1). This product is extensively used in cancer research to treat various types of cancer, such as breast cancer, colorectal cancer, and lung cancer. In this article, we will introduce the product's features and quality to help merchants make informed purchasing decisions.
Product Features
MK-1775 has several key features that make it a valuable product in the market. These are:
1. High Potency
MK-1775 has high potency and is a selective checkpoint kinase 1 (Chk1) inhibitor. This means that it can target specific cancer cells without damaging healthy cells. Its high potency has been demonstrated in preclinical models and clinical trials, where it has shown significant anti-tumor activity.
2. Versatility
MK-1775 has shown great versatility in treating various types of cancer. It has shown effectiveness in preclinical models of breast cancer, colorectal cancer, and lung cancer. Additionally, it has shown synergy with other drugs such as gemcitabine, topotecan, and 5-fluorouracil.
3. FDA Approval
MK-1775 is an FDA-approved drug, which means that it has undergone rigorous testing and has been proven to be safe and effective for use in humans.
Product Quality
In addition to its features, MK-1775 meets high-quality standards, which ensure that merchants receive top-quality products. Below are some factors that ensure product quality:
1. Manufacturing standards
Our manufacturing process adheres to strict standards set by the FDA and other regulatory authorities. We use state-of-the-art equipment and processes to ensure that our products meet the highest level of quality.
2. Quality control
Our team of professionals ensures that each batch of MK-1775 goes through rigorous quality control measures. This includes testing the product for purity, potency, and stability.
3. Packaging and labeling
We use carefully selected packaging materials that protect the product during shipping and storage. Additionally, our labeling meets all appropriate regulatory requirements and provides merchants with accurate product information.
Conclusion
MK-1775 CAS No.:955365-80-7 is an FDA-approved, high-potency, and selective CHK1 inhibitor that has demonstrated effectiveness in treating various types of cancer. Merchants can trust its quality, thanks to our adherence to strict manufacturing standards, quality control measures, and appropriate packaging and labeling. Choosing MK-1775 as a cancer treatment option can help enhance treatment effectiveness and improve patients' quality of life.
Chemical Structure : Adavosertib
CAS No.: 955365-80-7

Adavosertib(AZD-1775;MK-1775)
Catalog No.: URK-V1391 Only Used For Lab.
A potent and selective small-molecule inhibitor of Wee1 kinase with IC50 of 5.2 nM.
Biological Activity
A potent and selective small-molecule inhibitor of Wee1 kinase with IC50 of 5.2 nM; exhibits ATP-competitive and highly selective against other serine/threonine or tyrosine kinases; inhibits phosphorylation of CDC2 at Tyr15 in cells; potentiates tumor growth inhibition in vivo.
Lung Cancer
Phase 2 Clinical
Physicochemical Properties
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M.Wt |
500.595 |
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Formula |
C27H32N8O2 |
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CAS No. |
955365-80-7 |
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Storage |
Solide Powder -20 °C 3years; 4°C 2years |
In Solvent -80°C 6 Months -20°C 1 Months |
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Solubility |
10 mM in DMSO |
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Chemical Name |
3H-Pyrazolo[3,4-d]pyrimidin-3-one, 1,2-dihydro-1-[6-(1-hydroxy-1-methylethyl)-2-pyridinyl]-6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-2-(2-propen-1-yl)- |
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References
1. Hirai H, et al. Mol Cancer Ther. 2009 Nov;8(11):2992-3000.
2. Hirai H, et al. Cancer Biol Ther. 2010 Apr 1;9(7):514-22.
3. Bridges KA, et al. Clin Cancer Res. 2011 Sep 1;17(17):5638-48.
Note: All products of Ureiko are only used for scientific research or drug certificate declaration, and we do not provide products and services for any personal use!
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- Our customer service team is available to answer any questions or concerns you have about our products.
- We know that we only thrive if we can guarantee our combined rate competiveness and good quality advantageous at the same time for MK-1775 CAS No.:955365-80-7.
- Our products are made to withstand rigorous testing and use, ensuring accurate results every time.
- Based on the scientific concept of 'development comes from communication', we constantly provide customers with new products and high-quality services.
- Our experienced team is always available to answer any questions you may have.
- We know that to firmly attract customers and expand market share, we must be close to customers and provide them with better service.
- We use state-of-the-art equipment and facilities to ensure that our products are of the highest quality.
- We attach importance to the progress and development of technology, and continue to strengthen the scientific and technological team to meet the various requirements of customers, and our products have reached the international level. Our company has a good development thanks to the support and cooperation of friends from all walks of life.
- Our products are made with the environment in mind, using sustainable materials and manufacturing processes.
- The core of our corporate culture is teamwork. In our daily work, we emphasize that employees should communicate more, complain less, understand more and argue less.
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