
Description
G007-LK CAS No.:1380672-07-0 is a highly effective and versatile chemical compound that has a wide range of applications in various industries. It is a product that boasts of high purity, excellent solubility and stability, making it an ideal choice for manufacturers and suppliers.
One of the key aspects that make G007-LK an attractive option for merchants is its versatility as a compound. It has been proven to be highly effective in the manufacture of a wide range of products, including pharmaceuticals, agrochemicals, and cosmetics. As such, it is a product that appeals to merchants who want to expand the scope of their business operations.
Another aspect that makes G007-LK an attractive option is its unique chemical composition. Its structure is highly complex, allowing it to respond to a wide range of stimuli. This unique chemical composition also makes it resistant to degradation and external forces, ensuring that the final product is of the highest quality.
Furthermore, G007-LK is highly soluble, making it easy to mix with other compounds during the manufacturing process. This ability to dissolve easily also translates to the final product, ensuring that the end-user receives a product that is easy to use.
G007-LK is highly stable, making it an ideal choice for manufacturers who require a long shelf life for their products. This stability ensures that the final product remains potent and effective, even after extended periods of storage.
In addition to its impressive chemical properties, G007-LK is also highly cost-effective. Its high purity, unique chemical composition, and ease of use during the manufacturing process make it an affordable option for manufacturers and suppliers.
Merchants looking for a product that has been tested and proven to be highly effective can count on G007-LK to deliver the desired results. This chemical compound has been extensively tested and has been proven to meet the highest industry standards.
In conclusion, G007-LK CAS No.:1380672-07-0 is a highly versatile, stable, and cost-effective compound that is an ideal choice for merchants looking to expand their business operations. Its unique chemical composition, solubility, and stability make it highly effective in the manufacture of a wide range of products. Its affordability and high purity make it an attractive option for manufacturers and suppliers looking for a quality product. For more information about G007-LK, please don't hesitate to contact us.
Chemical Structure : G007-LK
CAS No.: 1380672-07-0

G007-LK(G007 LK;G007LK)
Catalog No.: URK-V1005 Only Used For Lab.
G007-LK is a potent, specific, metabolically stable TNKS1/2 inhibitor with IC50 of 46 nM and 25 nM, respectively.
Biological Activity
G007-LK is a potent, specific, metabolically stable TNKS1/2 inhibitor with IC50 of 46 nM and 25 nM, respectively; reduces Wnt/β-catenin signaling by preventing poly(ADP-ribosyl)ation-dependent AXIN degradation, thereby promoting β-catenin destabilization; effectively blocks ligand-driven Wnt/β-catenin signaling in cell culture and displays approximately 50% inhibition of APC mutation-driven signaling in most CRC cell lines, inhibits the g of mouse intestinal organoids cultured ex vivo with IC50 of 80 nM; inhibits in vivo tumor growth in a subset of APC-mutant CRC xenograft models.
Physicochemical Properties
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M.Wt |
529.958 |
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Formula |
C25H16ClN7O3S |
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CAS No. |
1380672-07-0 |
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Storage |
Solide Powder -20 °C 3years; 4°C 2years |
In Solvent -80°C 6 Months -20°C 1 Months |
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Solubility |
DMSO: ≥ 30 mg/mL |
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Chemical Name |
Benzonitrile, 4-[5-[(1E)-2-[4-(2-chlorophenyl)-5-[5-(methylsulfonyl)-2-pyridinyl]-4H-1,2,4-triazol-3-yl]ethenyl]-1,3,4-oxadiazol-2-yl]- |
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References
1. Voronkov A, et al. J Med Chem. 2013 Apr 11;56(7):3012-23.
2. Lau T, et al. Cancer Res. 2013 May 15;73(10):3132-44.
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