BMN 673 CAS No.:1207456-01-6

Introduction:

BMN 673, also known as talazoparib, is a potent and highly selective poly (ADP-ribose) polymerase (PARP) inhibitor. It has the ability to selectively kill cancer cells that have defective DNA repair pathways, such as those with BRCA1/2 mutations. Talazoparib was approved by the US FDA in 2018 for the treatment of metastatic breast cancer with BRCA mutations.

As a manufacturer, we are experienced in producing high-quality BMN 673 for global distribution. We strive to provide the highest quality products at the most competitive prices. We understand the importance of delivering a reliable and consistent supply of BMN 673 to our customers, which is why we have established a rigorous quality control system at every stage of our production process.

Product Features:

1. Highly selective PARP inhibitor - BMN 673 is a highly selective PARP inhibitor, which means it targets specific proteins within the cell that are involved in DNA repair. This makes it an effective treatment for cancer cells that have defective DNA repair pathways.

2. Potent and effective - BMN 673 has been shown to have potent antitumor activity in vitro and in vivo. It has been used in clinical trials for the treatment of various cancers, including breast cancer, ovarian cancer, and prostate cancer.

3. Oral administration - BMN 673 is available in oral capsule form, making it easy to administer and convenient for patients.

4. Approved by the US FDA - BMN 673 has been approved by the US FDA for the treatment of metastatic breast cancer with BRCA mutations. This indicates its safety and efficacy in the treatment of this specific type of cancer.

5. Minimal side effects - Data from clinical trials have shown that BMN 673 has a favorable safety profile, with minimal side effects reported.

Product Applications:

1. Treatment of breast cancer - BMN 673 is currently approved for the treatment of metastatic breast cancer with BRCA mutations. It has been shown to be effective in this patient population, improving progression-free survival and overall survival.

2. Treatment of ovarian cancer - BMN 673 has been studied in clinical trials for the treatment of ovarian cancer. It has shown promising results in improving progression-free survival in patients with BRCA mutations.

3. Treatment of other types of cancer - BMN 673 has also been studied in clinical trials for the treatment of other types of cancer, including prostate cancer and small cell lung cancer.

Conclusion:

As a leading manufacturer of BMN 673 in China, we are committed to providing high-quality products at competitive prices to our global customers. Our expertise in producing BMN 673, combined with our rigorous quality control system, ensures a reliable and consistent supply of this important cancer treatment. With its high selectivity, potency, and minimal side effects, BMN 673 has the potential to improve the lives of cancer patients worldwide.

Chemical Structure : Talazoparib

CAS No.: 1207456-01-6

 

Talazoparib(BMN-673; LT-673)

Catalog No.: URK-V911  Only Used For Lab.

Talazoparib (BMN673) is a highly potent, orally active PARP1/2 inhibitor.Talazoparib inhibits PARP1 and PARP2 enzyme activity with Kis of 1.2 nM and 0.87 nM, respectively. Talazoparib has antitumor activity

Biological Activity

Talazoparib (BMN-673) is a highly potent, orally active PARP1/2 inhibitor.Talazoparib inhibits PARP1 and PARP2 enzyme activity with Kis of 1.2 nM and 0.87 nM, respectively. Talazoparib has antitumor activity

Physicochemical Properties

References

URK-V911_COA

URK-V911_SDS

URK-V911_TDS

 

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