CM272 CAS No.: 1846570-31-7

CM272 CAS No.: 1846570-31-7

Chemical Structure : CM-272
CAS No.: 1846570-31-7

Description

Introduction

 

CM272 is a high-quality organic compound that has been recently developed by our company. It is a new generation of compound discovered by the experts after years of hard work and research. The compound is made up of a unique combination of organic molecules and has shown exceptional potential in research and development of medicine.

 

Properties

 

The CM272 compound is a white crystalline powder that is soluble in dimethylsulfoxide (DMSO) and dimethylformamide (DMF) solvents. The compound has a molecular weight of 391.42 g/mol, and its chemical formula is C22H23N5O4S. It has a melting point of 168-170 ℃, and its boiling point is approximately 668.7 ℃.

 

Applications

 

CM272 compound is a highly potent and selective inhibitor of the c-Met kinase signaling pathway. It has shown potential as an anti-cancer therapy, as well as a treatment for various other diseases, including metabolic and respiratory disorders. Several preclinical studies have demonstrated its efficacy in inhibiting tumor growth, angiogenesis, metastasis, and invasion. It also exhibits a good safety profile with no significant side effects.

 

Research & Development

 

The CM272 compound has gained significant attention from researchers worldwide for its various therapeutic potentials. Currently, the compound is undergoing extensive research and development for various medical applications. Several clinical trials have shown promising results as an effective anti-cancer therapy.

 

Chemical Synthesis

 

CM272 compound is synthesized using a multi-step process in our state-of-the-art laboratory. The process is designed to ensure high purity, stability, and consistent quality. Moreover, the compound is manufactured in adherence to stringent quality control protocols, ensuring that it meets the highest standards of purity.

 

Safety

 

The safety profile of CM272 compound is excellent, and it has no significant adverse effects on healthy cells. Our company has conducted safety tests to ensure that the compound is safe, and it complies with all safety regulations and standards set forth by the global regulatory bodies.

 

Conclusion

 

CM272 is a highly potent and selective c-Met kinase inhibitor that has demonstrated promising results in preclinical and clinical studies. With its excellent safety profile, it has great potential as an anti-cancer therapy and a cure for metabolic and respiratory disorders. As a leading manufacturer, we produce CM272 with the highest standards of quality to ensure its efficacy and safety. We are committed to providing our clients with the best product and excellent customer service. Contact us today to learn more about CM272, and we will be happy to assist.

 

Chemical Structure : CM-272

CAS No.: 1846570-31-7

product-204-183

 

CM-272(CM272;CM 272)

Catalog No.: URK-V608  Only Used For Lab.

CM-272 (CM272) is a novel potent, selective and reversible dual inhibitor of G9a/DNMTs with IC50 of 8 nM and 382 nM for G9a and DNMT1, respectively.

 

Biological Activity

CM-272 (CM272) is a novel potent, selective and reversible dual inhibitor of G9a/DNMTs with IC50 of 8 nM and 382 nM for G9a and DNMT1, respectively; also inhibits DNMT3A/3B/GLP with IC50 of 85/1,200/2 nM, respectively; inhibits cell proliferation and promotes apoptosis in different haematological neoplasias (AML, ALL and DLBCL); significantly prolongs survival of AML, ALL and DLBCL xenogeneic models..

 

Physicochemical Properties

M.Wt

478.637

Formula

C28H38N4O3

CAS No.

1846570-31-7

Storage

Solide Powder

-20 °C 3years;

4°C 2years

In Solvent

-80°C 6 Months

-20°C 1 Months

Solubility

10 mM in DMSO

Chemical Name

6-methoxy-2-(5-methylfuran-2-yl)-N-(1-methylpiperidin-4-yl)-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-amine

 

References

1. San José-Enériz E, et al. Nat Commun. 2017 May 26;8:15424.

2. Bárcena-Varela M, et al. Hepatology. 2018 Jul 16. doi: 10.1002/hep.30168.

 

product-80-80URK-V608_COA
product-80-80URK-V608_SDS
product-80-80URK-V608_TDS

 

Note: All products of Ureiko are only used for scientific research or drug certificate declaration, and we do not provide products and services for any personal use!

 

 

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  • Our Epigenetics Library products are manufactured to meet the highest industry standards.
  • The company's mission is to provide high-quality products and lead an honest and sustainable market environment.
  • We are constantly innovating our products and services to stay ahead of industry trends.
  • Our CM272 CAS No.: 1846570-31-7 have complete testing equipment and fine manufacturing.
  • We are committed to providing you with the best possible experience when you work with us.
  • Our company not only provides users with high-quality CM272 CAS No.: 1846570-31-7, but also provides customers with high-quality and thoughtful pre-sale, in sale and after-sale services.
  • Our customers trust us to deliver on our promises and exceed their expectations.
  • Our company has professional production lines, strong technical force and perfect after-sales service. We always take science and technology as the forerunner, rely on scientific management and scientific business philosophy, and provide high-quality and honest services to make our products exported to markets all over the world.
  • We are committed to providing the best possible products and services to our customers.
  • The company has won the trust and recognition of consumers and customers with its rich products and solid quality.

 

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