HC-070 CAS No.: 1628291-95-1

Chemical Structure : HC-070

CAS No.: 1628291-95-1

 

HC-070

Catalog No.: URK-V2509 Only Used For Lab.

HC-070 is a novel and potent inhibitor of TRPC4 and TRPC5 channels.

Biological Activity

HC-070 is a novel and potent inhibitor of TRPC4 and TRPC5 channels.
The mechanism of action of HC-070 involves selective inhibition of TRPC4 and TRPC5 channels by binding to a specific site on the inner pore domain of these channels. HC-070 has been shown to exhibit high selectivity towards TRPC4 and TRPC5 channels, with little or no effect on other TRPC subtypes or related ion channels. HC-070 also has good stability and bioavailability, making it a promising candidate for further development as a novel therapeutic agent.

Physicochemical Properties

References

1. Zitt C, et al. J Biol Chem. 2004;279(15):15234-15240.

2. Schindl R, et al. Br J Pharmacol. 2008;155(4):582-591.

3. Weiger TM, et al. Nat Chem Biol. 2012;8(12):1066-1073.

4. Han J, et al. Nat Commun. 2016;7:10853.

5. Kim BJ, et al. Nat Chem Biol. 2018;14(6):595-597.

URK-V2509_COA

URk-V2509_SDS

URK-V2509_TDS

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