HEC96719 CAS No.: 2181834-03-5

Chemical Structure : HEC96719

CAS No.: 2181834-03-5

 

HEC96719

Catalog No.: URK-V2516 Only Used For Lab.

HEC96719 is a novel potent activity against the important protein target histone deacetylase 6 (HDAC6). HDAC6 is known to play a key role in the regulation of cell proliferation, differentiation, and cell homeostasis.

Biological Activity

HEC96719 is a novel potent activity against the important protein target histone deacetylase 6 (HDAC6). HDAC6 is known to play a key role in the regulation of cell proliferation, differentiation, and cell homeostasis.
HEC96719 exhibits a unique mechanism of action in its ability to downregulate the expression of key pro-inflammatory cytokines, including TNF-α, IL-1β, and IL-6.

Physicochemical Properties

References

1. Stimson L, et al. Discovery of Novel Small Molecule Inhibitors of Histone Deacetylase-6 (HDAC6). J Med Chem. 2016 Oct 13; 59(19): 10562–10577.

2. Xiao Y, et al. HEC96719, a potent small molecule inhibitor of HDAC6, exhibits anti-inflammatory activity by downregulating TNF-α, IL-1β, and IL-6 expression. Eur J Pharmacol. 2020 Aug 15;880: 173145.

URK-V2516_COA

URk-V2516_SDS

URK-V2516_TDS

Hot Tags: HEC96719 CAS No.: 2181834-03-5, China HEC96719 CAS No.: 2181834-03-5, nf-?b pathway phosphorylation analysis, agonists in pharmaceutical research, inhibitors for tissue engineering, epigenetic library for epigenetic regulation of cell senescence, epigenetic library for epigenetic analysis of epigenetic therapeutics, inhibitors for pathogen recognition