Description
Chemical Structure : HEC96719
CAS No.: 2181834-03-5
HEC96719
Catalog No.: URK-V2516 Only Used For Lab.
HEC96719 is a novel potent activity against the important protein target histone deacetylase 6 (HDAC6). HDAC6 is known to play a key role in the regulation of cell proliferation, differentiation, and cell homeostasis.
Biological Activity
HEC96719 is a novel potent activity against the important protein target histone deacetylase 6 (HDAC6). HDAC6 is known to play a key role in the regulation of cell proliferation, differentiation, and cell homeostasis.
HEC96719 exhibits a unique mechanism of action in its ability to downregulate the expression of key pro-inflammatory cytokines, including TNF-α, IL-1β, and IL-6.
Physicochemical Properties
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M.Wt |
549.40 |
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Formula |
C29H22Cl2N2O5 |
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CAS No. |
2181834-03-5 |
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Appearance |
Solid |
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Storage |
Solide Powder -20 °C 3years; 4°C 2years |
In Solvent -80°C 6 Months -20°C 1 Months |
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Solubility |
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Chemical Name |
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References
1. Stimson L, et al. Discovery of Novel Small Molecule Inhibitors of Histone Deacetylase-6 (HDAC6). J Med Chem. 2016 Oct 13; 59(19): 10562–10577.
2. Xiao Y, et al. HEC96719, a potent small molecule inhibitor of HDAC6, exhibits anti-inflammatory activity by downregulating TNF-α, IL-1β, and IL-6 expression. Eur J Pharmacol. 2020 Aug 15;880: 173145.
URK-V2516_COA
URk-V2516_SDS
URK-V2516_TDS
Hot Tags: HEC96719 CAS No.: 2181834-03-5, China HEC96719 CAS No.: 2181834-03-5
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