Tipifarnib S Enantiomer CAS No.: 192185-71-0

Introduction:

Tipifarnib S Enantiomer CAS No.: 192185-71-0, is a chemical compound widely used in the pharmaceutical industry. It is an isomer of Tipifarnib, which is commonly known as R115777. Our company is a manufacturer located in China, and we supply quality Tipifarnib S Enantiomer to merchants worldwide.

What is Tipifarnib S Enantiomer?

Tipifarnib S Enantiomer is a selective farnesyltransferase inhibitor (FTI) that belongs to the class of antineoplastic agents. It is mainly used for the treatment of various types of cancer, including acute myeloid leukemia (AML), myelodysplastic syndromes (MDS), and lymphomas. The high purity and precise composition of Tipifarnib S Enantiomer make it an ideal choice for targeted cancer therapies.

Benefits of Tipifarnib S Enantiomer:

1. Effective cancer treatment - Tipifarnib S Enantiomer is highly effective in killing cancer cells by inhibiting farnesyltransferase. It is a targeted therapy that specifically targets cancer cells by preventing them from growing and dividing.

2. Minimal side-effects - Unlike traditional chemotherapy, Tipifarnib S Enantiomer has fewer side effects. It does not harm healthy cells or tissues, making it a safe choice for cancer treatment.

3. High purity and precision - Our company follows strict quality control guidelines to ensure that the product is of high purity and precise composition. This makes Tipifarnib S Enantiomer a reliable option for cancer treatment.

4. Competitive pricing - We offer competitive pricing that is accessible to all merchants. Our aim is to make high-quality cancer treatment accessible to everyone.

Uses of Tipifarnib S Enantiomer:

1. Acute myeloid leukemia (AML) - Tipifarnib S Enantiomer is used to treat AML, a type of cancer that affects the blood and bone marrow. It is an effective treatment option for patients who have relapsed or who are resistant to other treatments.

2. Myelodysplastic syndromes (MDS) - Tipifarnib S Enantiomer is also used to treat MDS, a group of disorders that affect the production of blood cells in the bone marrow. It can be used alone or in combination with other treatments.

3. Lymphomas - Tipifarnib S Enantiomer is used to treat lymphomas, a type of cancer that originates in the lymphatic system. It is used in combination with other chemotherapy agents.

Conclusion:

Tipifarnib S Enantiomer is an effective cancer treatment option that is safe and has minimal side effects. As a manufacturer, we follow strict quality control guidelines to ensure that our product is of high purity and precise composition. We offer competitive pricing to make high-quality cancer treatment accessible to everyone. We are committed to providing the best possible service to our clients, and we welcome inquiries from merchants worldwide.

Chemical Structure: Tipifarnib S enantiomer

CAS No.: 192185-71-0

 

Tipifarnib S enantiomer((S)-(-)-R-115777;IND-58359 S enantiomer)

Catalog No.: URK-V592 Only Used For Lab.

Tipifarnib S enantiomer (IND-58359 S enantiomer) is a potent and selective inhibitor of FTase (farnesyltransferase).

Biological Activity

Tipifarnib S enantiomer, the S-enantiomer of Tipifarnib, is a potent and selective inhibitor of FTase (farnesyltransferase); inhibits the farnesylation of lamin B and K-RasB peptide substrates with IC50s of 0.86 nM and 7.9 nM, respectively; no activity for PGGT1(IC50>50 uM); shows sensiticity for tumor cell lines bearing H-ras or N-ras mutations; inhibits the growth of tumors bearing mice and orally bioavailable. Tipifarnib S enantiomer is an inactive isomer
Blood Cancer

Physicochemical Properties

References

1. End DW, et al. Cancer Res. 2001 Jan 1; 61(1):131-7.

2. Kelland LR, et al. Clin Cancer Res. 2001 Nov; 7(11):3544-50.

3. Beaupre DM, et al. Mol Cancer Ther. 2004 Feb; 3(2):179-86.

URK-V592_COA

URK-V592_SDS

URK-V592_TDS

 

Note: All products of Ureiko are only used for scientific research or drug certificate declaration, and we do not provide products and services for any personal use!

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