HIF-2α-IN-2 CAS No.:1672666-82-8

HIF-2α-IN-2 CAS No.:1672666-82-8

Chemical Structure : HIF-2α-IN-2
CAS No.: 1672666-82-8

Description

HIF-2α-IN-2 CAS No.:1672666-82-8 – Introduction

 

HIF-2α-IN-2 CAS No.:1672666-82-8 is a product that is commonly used in biomedical research. It is also known as a hypoxia-inducible factor 2 alpha inhibitor. The product is used to study hypoxia inducible factors (HIFs), which are transcription factors that are essential in the adaptive response to low oxygen availability. This product is useful in studying HIF2α, which is implicated in various cancer types, including renal, hepatic, and some lung cancers.

 

As a manufacturer located in China, we offer this product to merchants outside of China. Our product is of high quality and has been tested for its efficacy before being released into the market. In this piece, we'll provide you with the necessary information about HIF-2α-IN-2 CAS No.:1672666-82-8, to help you understand how this product can be useful in your research studies.

 

Product Description

 

HIF-2α-IN-2 CAS No.:1672666-82-8 is a chemically synthesized inhibitor of hypoxia-inducible factor 2 alpha (HIF-2α). The product is supplied as a white to off-white powder, and the chemical formula is C28H29N3O2S2. The molecular weight is 511.68 g/mol.

 

The product is known to selectively bind to HIF-2α protein, usually based on a 100-microtiter ELISA method. HIF-2α-IN-2 CAS No.:1672666-82-8 is generally useful in researching HIF2α-mediated gene expression and can be used to investigate the therapeutic potential of HIF inhibition in pre-clinical and clinical settings.

 

Applications and Benefits

 

HIF-2α-IN-2 CAS No.:1672666-82-8 has numerous applications in medical research, especially in the study of hypoxia-inducible factors (HIFs). HIFs are transcription factors that are activated under hypoxic conditions to regulate various adaptive responses, including angiogenesis, erythropoiesis, and glycolysis.

 

HIF-2α has been implicated in various cancer types, including renal, hepatic, and some lung cancers. Suppression of HIF-2α has been shown to reduce tumor growth in preclinical studies. Therefore, HIF-2α-IN-2 CAS No.:1672666-82-8 can be used as a tool to study the therapeutic potential of HIF inhibition in preclinical and clinical studies.

 

Additionally, HIF-2α-IN-2 CAS No.:1672666-82-8 can be used to study HIF2α-mediated gene expression. HIF-2α has been shown to regulate gene expression in various tissues, including the liver, kidney, and brain. Therefore, HIF-2α-IN-2 CAS No.:1672666-82-8 can help researchers understand the role of HIF-2α in these tissues and develop new therapies to treat diseases associated with HIF-2α deregulation.

 

Product Quality and Safety

 

As a manufacturer located in China, we ensure that our products are of high quality and safe for use in biomedical research. Before releasing our products into the market, we thoroughly test them for efficacy and safety. Our HIF-2α-IN-2 CAS No.:1672666-82-8 product is no exception. It has been tested to ensure that it is of high quality and safe for use in biomedical research.

 

Our products are also manufactured under strict quality control measures to ensure consistency and reproducibility, thus making them ideal for use in medical research.

 

Conclusion

 

HIF-2α-IN-2 CAS No.:1672666-82-8 is a valuable tool in studying hypoxia-inducible factor 2 alpha (HIF-2α) in biomedical research. This product is chemically synthesized, and it is supplied as a white to off-white powder.

 

This product is useful in researching HIF2α-mediated gene expression, and it can also be used to investigate the therapeutic potential of HIF inhibition in preclinical and clinical settings. Additionally, our product is of high quality and safe for use in biomedical research.

 

As a manufacturer located in China, we offer this product to merchants outside of China, ensuring that our customers receive quality products that are useful in their research studies. If you are a biomedical researcher in need of high-quality HIF-2α-IN-2 CAS No.:1672666-82-8, contact us today, and we’ll supply you with the best quality product available.

 

Chemical Structure : HIF-2α-IN-2

CAS No.: 1672666-82-8

product-164-166

 

HIF-2α-IN-2

Catalog No.: UR<-V623 Only Used For Lab.

HIF-2α-IN-2 is a hypoxia-inducible factor (HIF-2α) inhibitor with IC50 of 16 nM in scintillation proximity assay, extracted from patent WO2015035223A1, Compound 232.

 

Biological Activity

HIF-2α-IN-2 is a hypoxia-inducible factor (HIF-2α) inhibitor with IC50 of 16 nM in scintillation proximity assay, extracted from patent WO2015035223A1, Compound 232.

 

Physicochemical Properties

M.Wt

365.35

Formula

C17H13F2NO4S

CAS No.

1672666-82-8

Storage

Solide Powder

-20 °C 3years;

4°C 2years

In Solvent

-80°C 6 Months

-20°C 1 Months

Solubility

10 mM in DMSO

Chemical Name

 

References

1. Yu-Ki Tahara, et al. J Am Chem Soc. 2018 Feb 14;140(6):2105-2114.

2. Qin S, et al. J Immunol. 2020 Oct 15;205(8):2231-2242.

3. Zhang L, et al. Redox Biol. 2021 Apr;40:101848.

 

product-80-80URK-V623_COA
product-80-80URK-V623_SDS
product-80-80URK-V623_TDS
 

Note: All products of Ureiko are only used for scientific research or drug certificate declaration, and we do not provide products and services for any personal use!

 

 

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  • We take great care in ensuring that our products meet the highest standards.
  • We have advanced production conditions and can meet the various needs of customers at any time, which enable us to have unparalleled advantages in the HIF-2α-IN-2 CAS No.:1672666-82-8 industry.

 

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