IPI549 CAS No.: 1693758-51-8

Introduction

Welcome to our product page! We are a manufacturer located in China, and we specialize in the production of various chemicals, including IPI549 CAS No.: 1693758-51-8. Our product is of high quality and is in great demand among merchants worldwide. In this product introduction, we will discuss the key aspects of our IPI549 product that will attract merchants.

Overview

IPI549 is a type of selective phosphoinositide 3-kinase gamma (PI3Kγ) inhibitor. It is an investigational molecule that has been developed for the treatment of various types of cancer. Studies have shown that PI3Kγ plays a vital role in tumor growth and metastasis. Therefore, the inhibition of PI3Kγ could be a promising therapeutic strategy for cancer treatment.

IPI549 has demonstrated potent anti-tumor activity in preclinical studies. It has shown to selectively inhibit PI3Kγ and suppress the growth of cancer cells. Moreover, it has shown to be effective in combination with other drugs, such as checkpoint inhibitors and chemotherapy.

Advantages

There are several advantages of our IPI549 product that will prove to be appealing to merchants seeking to buy it. Some of these advantages include:

1. High Quality - Our IPI549 product is of high quality and is manufactured using advanced techniques. Quality is our top priority, and we ensure that our product undergoes rigorous quality control measures.

2. Competitive Price - We understand the importance of pricing in the competitive market. Therefore, we offer our IPI549 product at a competitive price that meets market demands.

3. Large Production Capacity - We have a large production capacity, which enables us to supply merchants with the quantities they require. We can fulfil orders of any size ranging from a few grams to kilograms.

4. Customization - We offer customized packaging options to suit the specific requirements of merchants. This customization helps protect the product during transportation, ensuring it reaches the customer's destination in perfect condition.

Applications

IPI549 is a highly versatile product that has a wide range of applications. It is primarily used in cancer research and drug development. It can also be used as a tool for investigating the role of PI3Kγ in various biological processes. The following are some of the applications of our IPI549 product:

1. Cancer Research - Our IPI549 product has been extensively used in cancer research. It has shown promising results in inhibiting tumor growth and metastasis in various preclinical and clinical studies.

2. Drug Development - IPI549 is being investigated as an investigational drug for the treatment of various cancers. The product shows potential in combination with other drugs such as checkpoint inhibitors and standard chemotherapy.

3. Investigating Biological Processes - IPI549 is also used as a tool for investigating the role of PI3Kγ in various biological processes. It has proven to be an invaluable asset in cell signaling and pharmacology research.

Conclusion

In summary, IPI549 is a promising product that has demonstrated high efficacy in preclinical studies. It is a PI3Kγ inhibitor that shows great potential in the treatment of various cancers. Our product is of high quality and is competitively priced, making it an attractive choice for merchants seeking to purchase IPI549. We have a large production capacity and offer customized packaging options that can be tailored to meet specific needs. The product is highly versatile and is used in cancer research, drug development, and various other biological processes. We hope you consider our IPI549 product for your research and development needs.

Chemical Structure : IPI-549

CAS No.: 1693758-51-8

 

IPI-549(IPI549;Eganelisib)

Catalog No.: URK-V596 Only Used For Lab.

Eganelisib (IPI-549) is a potent, highly selective, orally active inhibitor of PI3Kγ with IC50 of 16 nM, displays >100-fold selectivity over other lipid and protein kinases (PI3Kα IC50=3.2 uM, PI3Kβ IC50=3.5 uM, PI3Kδ IC50>8.4 uM).

Biological Activity

Eganelisib (IPI-549) is a potent, highly selective, orally active inhibitor of PI3Kγ with IC50 of 16 nM, displays >100-fold selectivity over other lipid and protein kinases (PI3Kα IC50=3.2 uM, PI3Kβ IC50=3.5 uM, PI3Kδ IC50>8.4 uM).
Eganelisib (IPI-549) demonstrates excellent PI3Kγ potency (IC50=1.2 nM) and selectivity against other Class I PI3K isoforms (>146-fold) in cellular phospho-AKT assays, dose dependently inhibits PI3Kγ dependent bone marrow-derived macrophage (BMDM) migration.
Eganelisib (IPI-549) demonstrates favorable pharmacokinetic properties and robust inhibition of PI3K-γ mediated neutrophil migration in vivo.

Physicochemical Properties

References

1. Evans CA, et al. ACS Med Chem Lett. 2016 Jul 22;7(9):862-7.

2. De Henau O, et al. Nature. 2016 Nov 17;539(7629):443-447.

URK-V596_COA

URK-V596_SDS

URK-V596_TDS

 

Note: All products of Ureiko are only used for scientific research or drug certificate declaration, and we do not provide products and services for any personal use!

Why choose us?

• We pride ourselves on being a trusted supplier of PI3K/Akt/mTOR Pathway Library products and services.
• Human beings are great because of dreams, and enterprises are prosperous because of culture.
• We offer reliable and trustworthy PI3K/Akt/mTOR Pathway Library products and services at an affordable price.
• Over the years, we have been widely recognized by the market with high-quality IPI549 CAS No.: 1693758-51-8, reasonable prices as well as a highly responsible attitude.
• Our factory strives to produce PI3K/Akt/mTOR Pathway Library products that meet or exceed customer expectations.
• The company will always adhere to the strategic layout of returning to the country and expanding outward, and will always focus on becoming the builder and pioneer of IPI549 CAS No.: 1693758-51-8, the pioneer of new integration, and the entrepreneur of new industries.
• We are passionate about delivering the best possible PI3K/Akt/mTOR Pathway Library products and services to our clients.
• Innovation requires everyone to consciously struggle, be good at learning, thinking and cognitizing, find problems with heart, find the right solution and put it into practice. Innovation requires strategic thinking, dare to invest, dare to take risks, and establish a fault-tolerant mechanism to support innovation.
• We offer a wide range of professional PI3K/Akt/mTOR Pathway Library services to meet all your needs.
• Our IPI549 CAS No.: 1693758-51-8 has acquired a world-class reputation and, more importantly, we guarantee the quality of our products.

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