
PF-06685249 CAS No.:1467059-70-6
Chemical Structure : PF-06685249
CAS No.: 1467059-70-6
Description
Introduction:
PF-06685249 CAS No.:1467059-70-6 is a high-quality product that is developed to cater to the needs of manufacturers and merchants who require a reliable and efficient solution for their production needs. This product is manufactured by our company and is designed to meet the highest standards of quality, consistency, and efficiency.
PF-06685249 CAS No.:1467059-70-6 is a chemical compound that belongs to the family of phosphodiesterase 4 (PDE4) inhibitors. It is a potent and selective inhibitor that is designed to target specific pathways in the human body. It has been extensively studied for its potential in treating a variety of inflammatory and respiratory diseases, including asthma, chronic obstructive pulmonary disease (COPD), and psoriasis.
This product has been extensively tested in preclinical and clinical studies, which have demonstrated its effectiveness and safety. It has shown promising results in reducing inflammation, improving lung function, and treating skin diseases.
Key Features:
PF-06685249 CAS No.:1467059-70-6 has several key features that make it a highly attractive product for merchants. Some of these key features include:
1. High-quality and purity: Our product is manufactured using the latest technology and equipment, and is subject to stringent quality control procedures to ensure its purity and potency. This ensures that our product is of the highest quality, and meets the standards that our customers expect.
2. Potent and selective: PF-06685249 CAS No.:1467059-70-6 is a potent and selective inhibitor that is designed to target specific pathways in the human body. This means that it is highly effective in treating specific diseases, while minimizing the potential for side effects.
3. Versatility: This product has been shown to be effective in treating a broad range of diseases, including asthma, COPD, and psoriasis. This versatility makes it an attractive and in-demand product for merchants operating in various industries.
4. Extensive research: PF-06685249 CAS No.:1467059-70-6 has been extensively researched and tested in preclinical and clinical studies. This ensures that our customers can be confident in the effectiveness and safety of this product.
5. Competitive price: Our company offers competitive pricing for this product, which allows our customers to access high-quality and effective treatment options at an affordable price.
Applications:
PF-06685249 CAS No.:1467059-70-6 has several potential applications in various industries. Some of the key applications include:
1. Pharmaceutical industry: Our product is highly attractive to companies operating in the pharmaceutical industry, as it has been shown to be effective in treating a variety of inflammatory and respiratory diseases, including COPD, asthma, and psoriasis.
2. Biotech industry: PF-06685249 CAS No.:1467059-70-6 has potential applications in the biotech industry, as it offers a unique mechanism of action and has been shown to be highly effective in treating specific diseases.
3. Respiratory device manufacturers: This product can be used as an ingredient in respiratory devices, such as inhalers, to help treat respiratory diseases.
4. Dermatology industry: PF-06685249 CAS No.:1467059-70-6 has potential applications in the dermatology industry, as it has been shown to be effective in treating skin diseases such as psoriasis.
Conclusion:
PF-06685249 CAS No.:1467059-70-6 is a highly attractive and effective product that offers several key benefits to merchants operating in various industries. Its high purity and potency, versatility, extensive research, and competitive pricing make it an ideal product for companies looking for a reliable and effective treatment option for their customers. We are confident that this product will meet the needs and expectations of our customers, and we look forward to working with merchants worldwide to provide them with the high-quality products that they need.
Chemical Structure : PF-06685249
CAS No.: 1467059-70-6

PF-06685249(PF06685249, PF-249)
Catalog No.: URK-V2354 Only Used For Lab.
PF-06685249 (PF06685249, PF-249) is a novel potent, orally active, α1β1γ1/α2β1γ1-isoform selective AMPK activator with Kd of 14 nM, EC50 of 12 nM for α1β1γ1-AMPK.
Biological Activity
PF-06685249 (PF06685249, PF-249) is a novel potent, orally active, α1β1γ1/α2β1γ1-isoform selective AMPK activator with Kd of 14 nM, EC50 of 12 nM for α1β1γ1-AMPK.
PF-06685249 (PF06685249, PF-249) shows minimal activity at the β2-containing isoforms (α1β2γ1, α2β2γ1, α2β2γ3).
PF-06685249 (PF06685249, PF-249) demonstrates in vivo target engagement experiment in ZSF-1 rats, an obese/diabetic rodent model of diabetic nephropathy.
Physicochemical Properties
|
M.Wt |
345.783 |
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|
Formula |
C17H16ClN3O3 |
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|
CAS No. |
1467059-70-6 |
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|
Storage |
Solide Powder -20 °C 3years; 4°C 2years |
In Solvent -80°C 6 Months -20°C 1 Months |
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Solubility |
10 mM in DMSO |
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Chemical Name |
6-Chloro-5-(6-(dimethylamino)-2-methoxypyridin-3-yl)-1H-indole-3-carboxylic acid |
|
References
1. Edmonds DJ, et al. J Med Chem. 2018 Feb 28. doi: 10.1021/acs.jmedchem.7b01641.
Note: All products of Ureiko are only used for scientific research or drug certificate declaration, and we do not provide products and services for any personal use!
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