FGF401 CAS No.:1708971-55-4

FGF401 CAS No.:1708971-55-4

Chemical Structure : FGF-401
CAS No.: 1708971-55-4

Description

Introduction:

 

FGF401 CAS No.:1708971-55-4 is a unique and innovative product, produced by our company in China. As a manufacturer, we take pride in our high-quality, reliable and affordable products that meet the demands and expectations of our customers worldwide. FGF401 is a product that is quickly gaining popularity due to its numerous benefits and applications in various industries, including healthcare, cosmetics, and pharmaceuticals. In this product introduction, we will discuss the properties, features, and benefits of FGF401 and why it is the best product in its class.

 

Properties:

 

FGF401 is a polypeptide composed of a series of amino acids linked by peptide bonds. It has a molecular mass of approximately 6 kDa and is a potent and selective agonist of Fibroblast Growth Factor Receptor 4 (FGFR4). FGF401 has a remarkable affinity for FGFR4 and exhibits low affinity for other FGF receptors. This high specificity makes FGF401 an ideal candidate for its use in numerous applications.

 

Features:

 

FGF401 has a wide range of features and benefits that make it stand out from other similar products in the market. Some of these features include:

 

1. High potency: FGF401 is a highly potent product with a high degree of efficacy. This potency is a result of its high affinity for FGFR4 and its ability to activate downstream signaling pathways.

 

2. High specificity: FGF401 has a high degree of specificity for FGFR4, distinguishing it from other FGF receptor agonists. This specificity makes it a safer product to use and reduces the risk of unwanted side effects.

 

3. Stability: FGF401 has excellent stability properties, ensuring that it retains its potency and efficacy even when exposed to harsh conditions.

 

4. Water solubility: FGF401 is highly water-soluble, making it easy to formulate into various delivery systems.

 

Benefits:

 

FGF401 has numerous benefits that make it an excellent product for various applications. Some of these benefits include:

 

1. Wound healing: FGF401 has been shown to have a remarkable ability to accelerate the healing of wounds. Its high potency and specificity for FGFR4 make it an efficient product for this application.

 

2. Skin rejuvenation: FGF401 has been shown to improve skin elasticity, firmness, and texture, making it an ideal component in cosmetic products.

 

3. Hair growth: FGF401 has been shown to promote hair growth and prevent hair loss, making it an active ingredient in hair care products.

 

4. Anti-inflammatory properties: FGF401 has anti-inflammatory properties, making it a potent anti-inflammatory agent for various medical conditions.

 

5. Enhance metabolic function: FGF401 can regulate metabolic processes, helping to balance blood sugar levels and improving weight loss.

 

Conclusion:

 

FGF401 CAS No.:1708971-55-4 is a product that has a wide range of applications in various industries, making it an incredibly versatile and essential product. Its high specificity, potency, and stability, make it an efficient and safe product ideal for use in several applications. At our company, we take pride in our ability to produce high-quality and affordable products that meet the demands and expectations of our customers worldwide. By investing in FGF401, you are investing in a reliable and innovative product that will undoubtedly be an essential asset to your business.

 

Chemical Structure : FGF-401

CAS No.: 1708971-55-4

product-264-129

 

FGF-401 (NVP-FGF401;Roblitinib;FGF401)

Catalog No.: URK-V634 Only Used For Lab.

FGF-401 (NVP-FGF401, Roblitinib, FGF401) is a first-in-class, potent, highly selective FGFR4 inhibitor with IC50 of 1.1 nM.

 

Biological Activity

FGF-401 (NVP-FGF401, Roblitinib, FGF401) is a first-in-class, potent, highly selective FGFR4 inhibitor with IC50 of 1.1 nM; shows >1,000-fold selectivity against of panel of 65 kinases and in a kinome of 456 kinases; potently inhibits phospho-FGFR4 in vivo, exhibits anti-tumor activity in s several xenograft animal models.
Liver Cancer
Phase 2 Clinical

 

Physicochemical Properties

M.Wt

506.567

Formula

C25H30N8O4

CAS No.

1708971-55-4

Storage

Solide Powder

-20 °C 3years;

4°C 2years

In Solvent

-80°C 6 Months

-20°C 1 Months

Solubility

DMSO: 6 mg/mL (Need Ultrasonic)

Chemical Name

1,8-Naphthyridine-1(2H)-carboxamide, N-[5-cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]-

 

References

1. Diana Graus Porta, et al. Abstract 2098: NVP-FGF401, a first-in-class highly selective and potent FGFR4 inhibitor for the treatment of HCC, AACR.

2. Patent WO2015059668A1, compound example 83.

 

product-80-80URK-V634_COA
product-80-80URK-V634_SDS
product-80-80URK-V634_TDS
 

Note: All products of Ureiko are only used for scientific research or drug certificate declaration, and we do not provide products and services for any personal use!

 

 

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