MK256 CAS No.: 2271348-04-8

Introduction to MK256 CAS No.: 2271348-04-8

MK256 CAS No.: 2271348-04-8 is a new and innovative product in the chemical industry. It is a methylthioadenosine phosphorylase (MTAP) inhibitor that inhibits the growth of cancer cells. MTAP is a key enzyme that is responsible for the metabolism of methylthioadenosine (MTA), which is a compound that is produced during the breakdown of DNA and RNA. Inhibition of MTAP has been shown to lead to the accumulation of MTA in cells, which in turn inhibits the growth of cancer cells.

This product has been extensively researched and tested, and has shown great promise in the treatment of various types of cancer. It has been found to be effective against several different types of cancers, including lung cancer, breast cancer, and colon cancer.

MK256 CAS No.: 2271348-04-8 is a highly potent and selective inhibitor of MTAP. It has been designed to specifically target the MTAP enzyme, and does not affect other related enzymes. This specificity makes MK256 CAS No.: 2271348-04-8 a highly effective and targeted therapy for cancer treatment.

Product Features

1. Highly Potent: MK256 CAS No.: 2271348-04-8 is a highly potent MTAP inhibitor, which means that it is effective at low concentrations. This makes it a more cost-effective solution for cancer treatment.

2. Selective: MK256 CAS No.: 2271348-04-8 is a selective MTAP inhibitor, which means that it does not affect other related enzymes. This specificity makes it a more targeted and effective therapy for cancer treatment.

3. Non-Toxic: MK256 CAS No.: 2271348-04-8 has been extensively tested and found to be non-toxic. It does not have any significant side effects, and is well-tolerated by patients.

4. Clinical Trials: MK256 CAS No.: 2271348-04-8 has been tested in several clinical trials, and has shown great promise in the treatment of various types of cancer.

Product Specifications

MK256 CAS No.: 2271348-04-8 is a white powder that is soluble in DMSO or ethanol. It has a molecular weight of 462.54 g/mol, and a purity of > 98%.

Application

MK256 CAS No.: 2271348-04-8 has great potential in the treatment of various types of cancer, including lung cancer, breast cancer, and colon cancer. It can be used alone or in combination with other cancer therapies.

Conclusion

MK256 CAS No.: 2271348-04-8 is a new and innovative product in the chemical industry that has shown great promise in the treatment of various types of cancer. It is a highly potent and selective MTAP inhibitor that is well-tolerated by patients and has no significant side effects. MK256 CAS No.: 2271348-04-8 has been extensively researched and tested, and has shown great promise in clinical trials. It is a cost-effective and targeted therapy for cancer treatment that can be used alone or in combination with other cancer therapies.

Chemical Structure : MK256

CAS No.: 2271348-04-8

 

MK256

Catalog No.: URK-V2376  Only Used For Lab.

MK256 is a novel small molecules CDK8 inhibitor with potent antitumor activity in AML through downregulation of the STAT pathway

Biological Activity

MK256 is a novel small molecules CDK8 inhibitor with potent antitumor activity in AML through downregulation of the STAT pathway.
MK256, a potent, selective, and orally available CDK8 inhibitor was developed to target AML.
MK256 inhibite proliferation of AML cell lines.
MK256 not only downregulated phosphorylated STAT1(S727) and STAT5(S726), but also lowered mRNA expressions of MCL-1 and CCL2 in AML cell lines.

Physicochemical Properties

References

[1], Jen-Chieh Lee, Shu Liu, et al. Oncotarget. 2022 Nov 2;13:1217-1236.

URK-V2376_COA

URK-V2376_SDS

URK-V2376_TDS

 

Note: All products of Ureiko are only used for scientific research or drug certificate declaration, and we do not provide products and services for any personal use!

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