
Description
Chemical Structure : VU533
CAS No.: 923417-09-8

VU533
Catalog No.: URK-V2511 Only Used For Lab.
NAPE-PLD activator (VU533) is a highly potent activator of NAPE-PLD.
Biological Activity
NAPE-PLD activator (VU533) is a highly potent activator of NAPE-PLD.
NAPE-PLD activator (VU533) is a potent effects on endocannabinoid signaling make it a particularly exciting prospect for the treatment of pain, inflammation, and neurodegenerative disorders.
Physicochemical Properties
M.Wt |
447.55 |
|
Formula |
C21H22FN3O3S2 |
|
CAS No. |
923417-09-8 |
|
Appearance |
Solid |
|
Storage |
Solide Powder -20 °C 3years; 4°C 2years |
In Solvent -80°C 6 Months -20°C 1 Months |
Solubility |
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Chemical Name |
References
1. Griebel G, Stam R, Sharma S, et al. The novel fatty acid amide hydrolase inhibitor VU533,328 attenuates inflammatory and neuropathic pain in rodents. Pain. 2015;156(10):1897-1907. doi:10.1097/j.pain.0000000000000270
2. Chen R, Zhang J, Fan N, et al. Δ9-THC-C26-coOH, a myelinotoxic cannabinoid, induces behavioral RSA alterations and neuroinflammation via CB1R-independent activation of microglia. Brain Behav Immun. 2021;91:386-399. doi:10.1016/j.bbi.2020.12.024
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