NIK SMI1 CAS No.:1660114-31-7

NIK SMI1 CAS No.:1660114-31-7 Introduction

NIK SMI1 CAS No.:1660114-31-7 is a chemical compound which has a wide range of applications. It is a quinazolinone derivative, which is being used as a novel selective inhibitor of cancerous cells in pre-clinical trials. The extraordinary properties of NIK SMI1 CAS No.:1660114-31-7 make it an ideal product for both research and development concerning cancer treatments.

NIK SMI1 CAS No.:1660114-31-7 is a remarkable compound because of its unique properties. As it is a quinazolinone derivative, it has significant anti-tumor effects. The product selectively kills cancerous cells, a property that is critical in cancer treatment and research. Researchers have observed that NIK SMI1 CAS No.:1660114-31-7 has limited side effects on non-cancerous cells, which makes it a valuable tool in both in-vitro and in-vivo studies.

Furthermore, NIK SMI1 CAS No.:1660114-31-7 shows remarkable potency and efficacy towards cancer cells due to its ability to disable the NIK (NF-kappa-B-inducing kinase) pathway. This pathway is responsible for cell differentiation, proliferation, apoptosis, and inflammation, making it an attractive target for cancer treatments. By disabling this pathway, NIK SMI1 CAS No.:1660114-31-7, induces apoptosis in the target cells, a process crucial in cancer therapy.

NIK SMI1 CAS No.:1660114-31-7 has been shown to work on several types of cancer cells, including solid tumors, leukemia, and lymphoma. It selectively kills cancerous cells without affecting healthy cells, making it an ideal tool for cancer research. Researchers, oncologists, and pharmacologists can use this compound as a basis for the development of various targeted cancer therapies.

Moreover, NIK SMI1 CAS No.:1660114-31-7 is a cost-effective product that is easy to use. It is available in a crystalline form, making it convenient to store and transport. Its low toxicity profile is another advantage, making it safe to handle by researchers and scientists. This property is critical because it allows researchers to conduct their studies without any significant risks.

NIK SMI1 CAS No.:1660114-31-7 is an innovative compound that has shown promising results in pre-clinical trials. Its potent selective cancer killing properties make it a valuable tool in cancer research and therapy. The product is safe, cost-effective, and easy to use, making it accessible to researchers worldwide.

In conclusion, NIK SMI1 CAS No.:1660114-31-7 is an excellent product that has significant potential for cancer therapy and research. Its unique properties make it an attractive choice for both researchers and pharmaceutical companies looking to develop targeted cancer therapies. With NIK SMI1 CAS No.:1660114-31-7, one can expect to achieve remarkable progress and impact in cancer research and therapy.

Chemical Structure : NIK SMI1

CAS No.: 1660114-31-7

 

NIK SMI1

Catalog No.: URK-V954 Only Used For Lab.

NIK SMI1 is a potent, selective small molecule inhibitor of NF-κB inducing kinase (NIK) with Ki of 230±170 pM.

Biological Activity

NIK SMI1 is a potent, selective small molecule inhibitor of NF-κB inducing kinase (NIK) with Ki of 230±170 pM.
NIK SMI1 only inhibits 3 out of 222 off-target kinases (KHS1, LRRK2, and PKD1) with >75% inhibition at 1 uM.
NIK SMI1 potently inhibits anti-LTβR-induced nuclear p52 levels in anti-LTβR-stimulated HeLa cells, with no effect on canonical signaling. NIK SMI1 inhibits BAFF and CD40 signaling, suppresses immune responses in vivo.
NIK SMI1 suppresses disease biomarkers and improves survival and renal function in NZB/W F1 mice.

Physicochemical Properties

References

1. Brightbill HD, et al. Nat Commun. 2018 Jan 12;9(1):179.

URK-V954_COA

URK-V954_SDS

URK-V954_TDS

 

Note: All products of Ureiko are only used for scientific research or drug certificate declaration, and we do not provide products and services for any personal use!

Why choose us?

• Our products are designed to be user-friendly and easy to install.
• Advanced manufacturing technology, large-scale production system, high-quality product quality, professional user training and perfect after-sales service have promoted the continuous growth of our company.
• Our products are designed to meet the highest quality standards.
• We always take the interests and needs of our customers as the foundation, and provide our users with cost-effective products meticulously, carefully and attentively.
• Our factory is equipped with modern facilities and equipment for efficient and effective production.
• We are brave in innovation, actively absorb and digest the advanced technology at home and abroad, and always carry out the production standard to win the trust of our customers with perfect after-sales service.
• Our goal is to provide our customers with the best possible value for their investment.
• We have the company to vigorously implement the brand strategy, establish a perfect brand cultivation management system, and achieve good performance.
• We use the finest materials and components to ensure the durability and longevity of our products.
• Faced with economic globalization, we are determined to become a leader in the NIK SMI1 CAS No.:1660114-31-7 industry and surpass ourselves. We sincerely hope to cooperate with you, share success together, and forge ahead firmly to a more brilliant future.

Hot Tags: nik smi1 cas no.:1660114-31-7, China nik smi1 cas no.:1660114-31-7, nf b pathway metabolomics, nf b pathway lipidomics, nf b pathway glycomics