
Description
PTC596 CAS No.: 1610964-64-1 – Introduction
PTC596 is a novel and potent inhibitor of different types of cancer cells, and it is primarily used for cancer treatment. It works by targeting the abnormal cells in cancerous tumors, ultimately leading to the inhibition of their growth and destruction. Developed by PTC Therapeutics Inc., PTC596 has emerged as an innovative and cutting-edge drug which is in high demand by physicians and oncologists all over the world.
Here are some of the key features and benefits of PTC596 that make it an ideal choice for cancer treatment:
1. Highly effective: PTC596 has proven to be highly effective in inhibiting various types of cancer cells. In addition, it is also effective in delaying the growth of tumor sizes and reducing tumor aggressiveness. This makes it an ideal choice for cancer treatment options.
2. Easy to use: PTC596 is easy to administer, with patients typically taking it orally with water without any discomfort or inconvenience.
3. Precise targeting capability: PTC596 specifically targets cancer cells only, leaving normal healthy cells unharmed. This ensures that patients do not experience severe side effects during treatment.
4. Safe: PTC596 has been extensively tested and proven to be safe for human use, with minimal cases of adverse reactions reported.
5. Fast and significant results: PTC596 has been shown to produce fast and significant results in cancer treatment, allowing doctors to start seeing progress in their patients soon after administration.
6. Versatile: PTC596 can be used to treat various types of cancers, making it a versatile option for physicians and oncologists to prescribe.
Manufacturing, Quality Assurance, and Certification
Our products are manufactured under strict guidelines and protocols to ensure consistency and quality of the highest standards. In addition, we are committed to adhering to appropriate regulatory standards and obtaining necessary certifications to guarantee customer satisfaction and safety.
We work with a team of experienced and skilled professionals who ensure that our products are produced to the highest standards. We value our customers' trust and confidence in our products, maintaining quality by using only the best raw materials available.
We understand that quality control is critical, especially in the medical field. Therefore, we put rigorous control measures and checks in place throughout the manufacturing process, covering inspection of raw materials, production, and packaging to ensure the final product meets expected quality standards.
Our Certificates include but not limited to:
1. ISO Certification
2. GMP Certification
3. FDA and CE
4. Other quality certificates.
Conclusion
PTC596 is one of the most innovative cancer treatments available in the market, and we're excited to share it with our global customers. Our manufacturing processes are strictly regulated and adhere to the highest standards of quality control. We are committed to providing our customers with only the best, and we believe that our PTC596 product will meet and exceed their expectations. Our focus on quality and safety standards ensures that our customers can trust and rely on our products. We welcome customers from all over the world to purchase our PTC596 product and start their cancer treatment journey with us.
Chemical Structure : PTC-596
CAS No.: 1610964-64-1

PTC-596(Unesbulin, PTC 596, PTC596)
Catalog No.: URK-V617 Only Used For Lab.
PTC-596 (Unesbulin, PTC596) is a novel, orally active, small molecule inhibitor of BMI-1 that accelerates BMI-1 degradation, inhibits AML cells growth with IC50 of <100 nM.
Biological Activity
PTC-596 (Unesbulin, PTC596) is a novel, orally active, small molecule inhibitor of BMI-1 that accelerates BMI-1 degradation, inhibits AML cells growth with IC50 of <100 nM.
PTC-596 is a direct microtubule polymerization inhibitor.
PTC-596 reduces total BMI-1 protein levels by 87% and 61% in MOLM-13 and OCI-AML3 cells at 100 nM, induces apoptosis and reduces the levels of ubiquitylated histone H2A.
PTC-596 downregulates MCL-1 and induces p53-independent mitochondrial apoptosis in acute myeloid leukemia progenitor cells.
Physicochemical Properties
|
M.Wt |
420.347 |
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Formula |
C19H13F5N6 |
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CAS No. |
1610964-64-1 |
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|
Storage |
Solide Powder -20 °C 3years; 4°C 2years |
In Solvent -80°C 6 Months -20°C 1 Months |
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Solubility |
10 mM in DMSO |
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Chemical Name |
5-fluoro-2-(6-fluoro-2-methyl-1H-benzo[d]imidazol-1-yl)-N4-(4-(trifluoromethyl)phenyl)pyrimidine-4,6-diamine |
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References
1. Nishida Y, et al. Blood Cancer J. 2017 Feb 17;7(2):e527.
2, Eberle-Singh JA, et al. Clin Cancer Res. 2019 Jun 7. pii: clincanres.3281.2018. doi: 10.1158/1078-0432.CCR-18-3281.
3, Maeda A, et al. Oncotarget. 2018 Jun 19;9(47):28547-28560.
Note: All products of Ureiko are only used for scientific research or drug certificate declaration, and we do not provide products and services for any personal use!
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- We are committed to providing outstanding customer service when it comes to our Wnt/Notch/Hedgehog Library products.
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- In the broader market of the future, we hone our technology to become more mature, thus reducing the cost of our PTC596 CAS No.:1610964-64-1.
- At our factory, we take pride in our high-quality Wnt/Notch/Hedgehog Library products.
- Our company has a pioneering and innovative spirit and an infinite love for PTC596 CAS No.:1610964-64-1, and we regard the continuous development of employees, products, and the industry as our own responsibility. With a unique pool of shared knowledge, experience, and talent, we continually drive new technology development and innovation.
- Our Wnt/Notch/Hedgehog Library products are durable and designed to perform under harsh conditions.
- To get the stage of realizing dreams of our employees!
- Our Wnt/Notch/Hedgehog Library products conform to the highest industry standards.
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