ARV766 CAS No.: 2750830-09-0

Chemical Structure : ARV766

CAS No.: 2750830-09-0

 

ARV766

Catalog No.: URK-V2520 Only Used For Lab.

ARV766 is a selective inhibitor of the Wnt/beta-catenin signaling pathway, a well-known pathway that plays a crucial role in the regulation of cell proliferation, differentiation, and survival.

Biological Activity

ARV766 is a selective inhibitor of the Wnt/beta-catenin signaling pathway, a well-known pathway that plays a crucial role in the regulation of cell proliferation, differentiation, and survival.
ARV766 has been shown to inhibit the activity of beta-catenin, a critical component of the Wnt/beta-catenin pathway, leading to the downregulation of downstream targets involved in cell growth and survival.

Physicochemical Properties

References

1. Li, J. et al. (2017). Discovery and Development of Small Molecule Modulators of Wnt/beta-Catenin Signaling. Current medicinal chemistry, 24(32), 3584–3620.

2. Jang, G.B. et al. (2015). ARV-825, an Adaptable ARV-771 Derivative, Simultaneously Targets AR/BRD4 and Vulnerable Cancer Pathways. Cancer cell, 27(4), 678–693.

3. Zhang, X. et al. (2018). Antitumor activity of ARV-825, a BRD4/BET inhibitor, in BRG1-deficient cancer cells. Cell death & disease, 9(3), 310.

URK-V2520_COA

URk-V2520_SDS

URK-V2520_TDS

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