AB928 CAS No.:2239273-34-6

AB928 CAS No.:2239273-34-6

Chemical Structure : Etrumadenant
CAS No.: 2239273-34-6

Description

AB928 CAS No.:2239273-34-6 – A Revolutionary Solution for Cancer Treatment

 

As a leading pharmaceutical manufacturer based in China, we specialize in providing high-quality and clinically-proven products that cater to the medical needs of our global customers. Our latest product – AB928, CAS No.:2239273-34-6 – is a groundbreaking solution that offers a promising new approach to cancer treatment.

 

What is AB928?

 

AB928 is a small molecule dual inhibitor that targets two key metabolic pathways in cancer cells – the adenosine signaling and the IDO pathway. By blocking these pathways, it helps to reinvigorate the immune system and prevent cancer cells from spreading and multiplying.

 

Benefits of AB928

 

Studies have shown that AB928 has numerous benefits for cancer patients. Some of the key advantages are:

 

1. Enhanced anti-tumor activity – The dual inhibition of adenosine signaling and IDO pathway enables AB928 to enhance the anti-tumor activity of immune cells, thereby improving the effectiveness of cancer treatment.

 

2. Improved immunological memory – AB928 also promotes immunological memory, which means that the immune system can continue to recognize and attack cancer cells even after treatment has ended.

 

3. Minimal side effects – Unlike many traditional cancer therapies, AB928 has demonstrated minimal side effects in preclinical studies. This makes it a safer and more tolerable treatment option for cancer patients.

 

Application of AB928

 

AB928 has shown great potential in the treatment of a wide range of solid tumors, including melanoma, colorectal cancer, pancreatic cancer, lung cancer, and many more. It can be used as a monotherapy or in combination with other cancer therapies to enhance their effectiveness.

 

Our quality guarantee

 

At our facility in China, we strictly adhere to international standards of quality control to ensure the purity, potency, and safety of our products. Our team of experienced scientists and technicians uses state-of-the-art equipment and techniques to perform rigorous testing and analysis at every stage of the manufacturing process. We are committed to providing our global customers with products that meet and exceed their expectations.

 

Conclusion

 

AB928 represents a new hope for cancer patients around the world. Its mechanism of action, combined with its proven safety and effectiveness, makes it a promising option for cancer patients who are looking for a better alternative to traditional cancer therapies. We invite interested merchants to contact us to learn more about AB928 and how to purchase this innovative drug.

 

Chemical Structure : Etrumadenant

CAS No.: 2239273-34-6

product-289-123

 

Etrumadenant(AB928, AB-928, AB 928)

Catalog No.: URK-V688 Only Used For Lab.

Etrumadenant (AB928) is a potent, dual antagonist of the A2aR and A2bR adenosine receptors with Kb of 1.5 and 2.0 nM, respectively.

 

Biological Activity

Etrumadenant (AB928) is a potent, dual antagonist of the A2aR and A2bR adenosine receptors with Kb of 1.5 and 2.0 nM, respectively.
AB928 displays high selectivity towards related receptors (A1R, A3R, CD73, CD39, NTPDase 2/3).
AB928 is a potent inhibitor of NECA-mediated A2aR activation on cell lines, potently reverses adenosine-mediated CD8+ T cell suppression, potently inhibits cAMP-mediated pCREB activation in human leukocyte populations in whole blood.
AB928 inhibits tumor micro-environment adenosine generation and signaling for the treatment of cancer.

 

Physicochemical Properties

M.Wt

426.484

Formula

C23H22N8O

CAS No.

2239273-34-6

Storage

Solide Powder

-20 °C 3years;

4°C 2years

In Solvent

-80°C 6 Months

-20°C 1 Months

Solubility

10 mM in DMSO

Chemical Name

3-(2-amino-6-(1-((6-(2-hydroxypropan-2-yl)pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)pyrimidin-4-yl)-2-methylbenzonitrile

 

References

1, Seitz L, et al. Invest New Drugs. 2019 Aug;37(4):711-721.

 

product-80-80URK-V688_COA
product-80-80URK-V688_SDS
product-80-80URK-V688_TDS

 

Note: All products of Ureiko are only used for scientific research or drug certificate declaration, and we do not provide products and services for any personal use!

 

 

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  • Our Epigenetics Library products are designed to provide accurate and reliable data analysis.
  • Our advanced production equipment and strict quality assurance system provide a solid guarantee for the stable performance of our AB928 CAS No.:2239273-34-6.
  • Our Epigenetics Library products are backed by a quality guarantee.
  • We are well aware that to grasp product quality, we must first improve quality awareness. Employees who do not pay attention to product quality cannot produce good products.
  • We offer fast and efficient shipping services to ensure timely delivery of your products.
  • We operate our business at an international level and have international expertise and technology.
  • Our Epigenetics Library products are used by top scientists and researchers around the world.
  • We are better serving customers with high cost-effective products, professional services, determined and courageous efforts.
  • Our Epigenetics Library products are designed to streamline your research processes.
  • We continue to develop or introduce new products to enhance our market impact.

 

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