PF-04418948 CAS No.:1078166-57-0

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Chemical Structure : PF-04418948

CAS No.: 1078166-57-0

 

PF-04418948

Catalog No.: URK-V649 Only Used For Lab.

PF-04418948 (PF 04418948) is a novel potent and selective prostaglandin EP2 receptor antagonist.

Biological Activity

PF-04418948 (PF 04418948) is a novel potent and selective prostaglandin EP2 receptor antagonist; inhibits prostaglandin E(2)(PGE(2))-induced increase in cAMP in cells with a functional K(B) value of 1.8 nM; attenuates the butaprost-induced cutaneous blood flow response in rats; orally active.
Other Indication
Phase 1 Clinical

Physicochemical Properties

References

1. af Forselles KJ, et al. Br J Pharmacol. 2011 Dec;164(7):1847-56.

2. Birrell MA, et al. Br J Pharmacol. 2013 Jan;168(1):129-38.

3. Kach J, et al. J Biol Chem. 2014 Mar 14;289(11):7505-13.

URK-V649_COA

URK-V649_SDS

URK-V649_TDS

 

Note: All products of Ureiko are only used for scientific research or drug certificate declaration, and we do not provide products and services for any personal use!

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